219096
D -天冬氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸
Product Name
D -天冬氨酸, ReagentPlus®, 99%
质量水平
产品线
ReagentPlus®
方案
99%
表单
powder
旋光性
[α]20/D −24°, c = 2.3 in 6 M HCl
光学纯度
ee: 98% (GLC)
反应适用性
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
应用
peptide synthesis
SMILES字符串
N[C@H](CC(O)=O)C(O)=O
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChI key
CKLJMWTZIZZHCS-UWTATZPHSA-N
基因信息
rat ... Slc1a3(29483)
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应用
- 代谢组学分析鉴定差异代谢物作为急性心肌梗死的生物标志物：这项研究利用代谢组学来鉴定急性心肌梗死的生物标志物，展示了D-天冬氨酸在氨基酸代谢中的作用及其潜在的诊断应用。（Zhou等人，2024年）。
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Edi Erwan et al.
Amino acids, 43(5), 1969-1976 (2012-04-03)
Intracerebroventricular (i.c.v.) administration of L-aspartate (L-Asp) attenuates stress responses in neonatal chicks, but the mechanism has not been clarified. In the present study, three behavioral experiments were carried out under socially isolated stressful conditions exacerbated by the use of corticotrophin-releasing
Nobutoshi Ota et al.
Amino acids, 43(5), 1873-1886 (2012-08-09)
D-Aspartate (D-Asp) is an endogenous amino acid in the central nervous and reproductive systems of vertebrates and invertebrates. High concentrations of D-Asp are found in distinct anatomical locations, suggesting that it has specific physiological roles in animals. Many of the
Yuichi Kaji et al.
The British journal of ophthalmology, 96(8), 1127-1131 (2012-06-15)
Gelatinous drop-like corneal dystrophy (GDLD), also known as familial subepithelial corneal amyloidosis, is an autosomal recessive disorder that causes progressive corneal opacity due to accumulation of amyloid fibrils in the corneal stroma. Genetic analyses have revealed that a mutation in
Tadatoshi Kinouchi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3349-3352 (2011-09-29)
The formation and accumulation of D-aspartate residue (D-Asp) in proteins caused by oxidative stress leads to dysfunction and/or denaturation of proteins, and is consequently responsible for aging-related misfolding diseases such as cataracts, prion disease, and Alzheimer's disease. We sought to
Francesco Errico et al.
Amino acids, 43(5), 1861-1871 (2012-08-02)
Free D-aspartate (D-Asp) occurs in substantial amounts in the brain at the embryonic phase and in the first few postnatal days, and strongly decreases in adulthood. Temporal reduction of D-Asp levels depends on the postnatal onset of D-aspartate oxidase (DDO)
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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