Quality Level
assay
99%
form
liquid
refractive index
n20/D 1.485 (lit.)
bp
144 °C (lit.)
mp
−19 °C (lit.)
solubility
water: insoluble
density
1.802 g/mL at 25 °C (lit.)
functional group
bromo, fluoro
SMILES string
Fc1cc(F)c(Br)cc1F
InChI
1S/C6H2BrF3/c7-3-1-5(9)6(10)2-4(3)8/h1-2H
InChI key
DVTULTINXNWGJY-UHFFFAOYSA-N
General description
1-Bromo-2,4,5-trifluorobenzene undergoes Br-Mg-exchange reaction with i-PrMgBr in THF to yield organomagnesium compound.
Application
1-Bromo-2,4,5-trifluorobenzene has been used in the synthesis of:
- 3-ethenyl, 3-ethynyl, 3-aryl and 3-cyclopropyl-2,4,5-trifluorobenzoic acids
- 3-bromo-2,5,6-trifluorobenzoic acid and 2,4,5-trifluorobenzoic acid
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
132.8 °F - closed cup
flash_point_c
56 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
3-Ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl-2, 4, 5-trifluorobenzoic acids: Useful intermediate in the synthesis of quinolone antibacterials.
Turner WR and Suto MJ.
Tetrahedron Letters, 34(2), 281-284 (1993)
Bromine-magnesium-exchange as a general tool for the preparation of polyfunctional aryl and heteroaryl magnesium-reagents.
Abarbri M, et al.
Tetrahedron Letters, 40(42), 281-284 (1999)
A dramatic solvent effect during aromatic halogen-metal exchanges. Different products from lithiation of polyfluorobromobenzenes in ether and tetrahydrofuran.
Bridges AJ, et al.
The Journal of Organic Chemistry, 55(2), 773-775 (1990)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 247979-5G | 04061837071898 |