283746
4-(氨甲基)苯甲酸
97%, for peptide synthesis
别名:
PAMBA
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关于此项目
线性分子式:
H2NCH2C6H4CO2H
化学文摘社编号:
分子量:
151.16
Beilstein:
1100606
EC 号:
MDL编号:
UNSPSC代码:
12352106
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
产品名称
4-(氨甲基)苯甲酸, 97%
质量水平
方案
97%
表单
powder
反应适用性
reaction type: solution phase peptide synthesis
mp
≥300 °C (lit.)
应用
peptide synthesis
SMILES字符串
NCc1ccc(cc1)C(O)=O
InChI
1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
InChI key
QCTBMLYLENLHLA-UHFFFAOYSA-N
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应用
4-（氨基甲基）苯甲酸（PAMBA）可用于合成：
- 钴羧酸膦酸酯。
- Apoptozole（Az），具有促进突变囊性纤维化跨膜传导调节因子（CFTR）氯通道活性的膜运输的细胞效力。
- 环肽，由 L-谷氨酸和 3-氨基苯甲酸组成，可用作各种阳离子和阴离子的受体。
- 生物活性肽，具有有效的 GPR54（G 蛋白偶联受体）激动活性。
其他说明
4-（氨基甲基）苯甲酸也是一种抗出血剂，用于治疗内出血。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Carlos F R A C Lima et al.
The journal of physical chemistry. A, 111(42), 10598-10603 (2007-10-05)
The standard (p0 = 0.1 MPa) molar enthalpies of combustion of six aminomethylbenzoic acids were measured at T = 298.15 K by static bomb calorimetry. With these values, the standard molar enthalpies of formation in the crystalline state were obtained.
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Cho H J, et al.
Journal of the American Chemical Society, 133(50), 20267-20276 (2011)
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Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (1)(1), 62-65 (1993-01-01)
The influence of protease-inhibiting preparations on the development of humoral immune response in diseases involving the development of secondary immunodeficiency (experimentally induced acute pancreatitis and staphylococcal infection) has been studied. Five injections of contrycal and epsilon-aminocaproic acid (epsilon-ACA), starting from
M N Iakushenko et al.
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The examination of 49 newborn infants revealed that at the early neonatal period the character of the microbial colonization of the intestine depended on the kind of perinatal pathology: in lesions of the central nervous system and conjugation jaundice the
Sandra Osburn et al.
Rapid communications in mass spectrometry : RCM, 21(21), 3409-3419 (2007-09-29)
Formation of [bn+17+cat]+ is a prominent collision-induced dissociation (CID) pathway for Li+- and Na+-cationized peptides. Dissociation of protonated and Ag+-cationized peptides instead favors formation of the rival bn+/[bn-1+cat]+ species. In this study the influence of a 4-aminomethylbenzoic acid (4AMBz) residue
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