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Merck
CN

289647

3-氨基-4-羟基苯甲酸

97%, for peptide synthesis

别名:

4-Hydroxy-3-aminobenzoic acid

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关于此项目

线性分子式:
H2NC6H3(OH)CO2H
化学文摘社编号:
分子量:
153.14
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352106
EC Number:
216-390-2
MDL number:
Beilstein/REAXYS Number:
972238
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产品名称

3-氨基-4-羟基苯甲酸, 97%

InChI key

MRBKRZAPGUCWOS-UHFFFAOYSA-N

InChI

1S/C7H7NO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,8H2,(H,10,11)

SMILES string

Nc1cc(ccc1O)C(O)=O

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

208 °C (dec.) (lit.)

application(s)

peptide synthesis

Quality Level

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hirokazu Suzuki et al.
Journal of bacteriology, 189(5), 2155-2159 (2006-12-13)
An arylamine N-acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct from other eukaryotic and bacterial NATs in that it acetylated various 2-aminophenol derivatives more effectively than
Christian Gerecke et al.
Epigenetics, 15(3), 307-322 (2019-09-12)
Mutations in the enzyme isocitrate dehydrogenase 1 (IDH1) lead to metabolic alterations and a sustained formation of 2-hydroxyglutarate (2-HG). 2-HG is an oncometabolite as it inhibits the activity of α-ketoglutarate-dependent dioxygenases such as ten-eleven translocation (TET) enzymes. Inhibitors of mutant
Experience with cheetan in management of HIV infection.
J Chege et al.
East African medical journal, 74(7), 460-461 (1997-07-01)
Hirokazu Suzuki et al.
The Journal of antibiotics, 60(6), 380-387 (2007-07-10)
In grixazone biosynthesis by Streptomyces griseus, a key intermediate 3-amino-4-hydroxybenzoic acid (3,4-AHBA) is converted to another key intermediate 3-amino-4-hydroxybenzaldehyde (3,4-AHBAL). Two genes griC and griD in the grixazone biosynthesis gene cluster were found to be responsible for this conversion, because
Hirokazu Suzuki et al.
The Journal of biological chemistry, 281(48), 36944-36951 (2006-09-28)
The shikimate pathway, including seven enzymatic steps for production of chorismate via shikimate from phosphoenolpyruvate and erythrose-4-phosphate, is common in various organisms for the biosynthesis of not only aromatic amino acids but also most biogenic benzene derivatives. 3-Amino-4-hydroxybenzoic acid (3,4-AHBA)

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