Merck
CN

292915

Sigma-Aldrich

2-吡咯烷酮-5-羧酸

99%

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别名:
DL-2-吡咯烷酮-5-羧酸, DL-焦谷氨酸
Empirical Formula (Hill Notation):
C5H7NO3
CAS号:
分子量:
129.11
Beilstein:
82134
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

reaction suitability

reaction type: solution phase peptide synthesis

mp

183-185 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)C1CCC(=O)N1

InChI

1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)

InChI key

ODHCTXKNWHHXJC-UHFFFAOYSA-N

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此商品
PHR2817217700A6553
2-Pyrrolidone-5-carboxylic acid 99%

Sigma-Aldrich

292915

2-吡咯烷酮-5-羧酸

Pyroglutamic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2817

L-焦谷氨酸

DL-2-Aminocaprylic acid 99%

Sigma-Aldrich

217700

DL -2-氨基辛酸

mp

183-185 °C (lit.)

mp

160-163 °C (lit.)

mp

260 °C (dec.) (lit.)

mp

-

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

-

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

-

application(s)

peptide synthesis

application(s)

-

application(s)

peptide synthesis

application(s)

-

一般描述

DL-焦谷氨酸在不对称合成中用作手性合成砌块和手性助剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Pyroglutamic acid: a versatile building block in asymmetric synthesis
C Najera, et al.
Tetrahedron Asymmetry, 10, 2245-2303 (1999)
Stefania Perticaroli et al.
Biochimica et biophysica acta. Biomembranes, 1861(2), 403-409 (2018-11-23)
The superficial layer of the skin, the stratum corneum (SC), consists of corneocytes surrounded by lipid regions and acts as a protective barrier for the body against water loss, toxic agents and microorganisms. As most substances permeate the stratum corneum
Chien-Ming Hsieh et al.
Pharmaceutics, 12(6) (2020-06-18)
Extracellular matrix (ECM) hydrogel can create a favorable regenerative microenvironment and act as a promising dressing for accelerating the healing of diabetic wound. In this study, a simple and effective decellularization technique was developed and optimized to obtain acellular extracellular
Andres Gil et al.
Journal of pharmaceutical and biomedical analysis, 160, 289-296 (2018-08-17)
Oxidative stress is suggested to play an important role in several pathophysiological conditions. A recent study showed that decreasing 5-oxoproline (pyroglutamate) concentration, an important mediator of oxidative stress, by over-expressing 5-oxoprolinase, improves cardiac function post-myocardial infarction in mice. The aim
Tetsuyuki Takahashi et al.
Biochemical and biophysical research communications, 516(2), 388-396 (2019-06-21)
Inhibition of prostaglandin E2 signaling via EP2/EP4 prostanoid receptors suppresses Insulin-like growth factor (IGF)-1-induced proliferation of pancreatic cancer BxPC-3 cells. To better understand the mechanism of EP2/EP4 signaling for controlling cell proliferation, we performed metabolome analyses in BxPC-3 cells treated with IGF-1

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