质量水平
方案
99%
表单
liquid
折射率
n20/D 1.305 (lit.)
沸点
142 °C (lit.)
密度
1.93 g/mL at 25 °C (lit.)
官能团
bromo
fluoro
SMILES字符串
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
InChI
1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
InChI key
WTWWXOGTJWMJHI-UHFFFAOYSA-N
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一般描述
1-溴十七氟辛烷（全氟辛基溴）是一种全氟化碳。使用精氨酸-甘氨酸-天冬氨酸 (RGD) 多肽对全氟辛基溴的聚乙二醇化聚酯纳米胶囊进行表面修饰，用于肿瘤成像。全氟辛基溴纳米胶囊已被开发作为超声和磁共振成像 (MRI) 的双重造影剂。
应用
1-溴十七氟辛烷（全氟辛基溴）可作为氟-19 磁共振成像血管系统造影剂或用于合成氧载体。它也被用作血液替代品乳剂中的氧载体。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
H K Lee et al.
Journal of magnetic resonance imaging : JMRI, 2(1), 53-61 (1992-01-01)
Perfluorocarbons such as perfluoroctylbromide (PFOB) can be used as contrast agents in the vascular system for fluorine-19 magnetic resonance imaging or as synthetic oxygen carriers. F-19 imaging has been proposed for studying the vascular system, capillary flow, tissue perfusion, and
Qiang Tan et al.
Tissue engineering. Part A, 15(9), 2471-2480 (2009-03-19)
The biological effect of the perfluorocarbon-based artificial oxygen carrier (Oxygent) was investigated in tissue-engineered trachea (TET) construction. Media supplemented with and without 10% Oxygent were compared in all assessments. Partial tissue oxygen tension (PtO(2)) was measured with polarographic microprobes; epithelial
Alexander-Wigbert K Scholz et al.
Anesthesia and analgesia, 110(6), 1661-1668 (2010-05-08)
Functional magnetic resonance imaging (fMRI) of fluorine-19 allows for the mapping of oxygen partial pressure within perfluorocarbons in the alveolar space (Pao(2)). Theoretically, fMRI-detected Pao(2) can be combined with the Fick principle approach, i.e., a mass balance of oxygen uptake
Odile Diou et al.
Biomaterials, 33(22), 5593-5602 (2012-05-12)
PLGA-PEG nanocapsules containing a liquid core of perfluorooctyl bromide were synthesized by an emulsion-evaporation process and designed as contrast agents for (19)F MRI. Physico-chemical properties of plain and PEGylated nanocapsules were compared. The encapsulation efficiency of PFOB, estimated by (19)F
Sheng Wang et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 31(10), 1718-1720 (2011-10-27)
To investigate the effect of temperature on the partition coefficient of isoflurane and sevoflurane in perflurocarbonate emulsion (Oxygent(TM)). The partition coefficients of isoflurane and sevoflurane in perflurocarbonate emulsion (Oxygent(TM)) were measured at different temperatures (4, 22, 27, 32 and 37
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