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343862

1-溴七氟辛烷

Name: 1-溴七氟辛烷
Brand: ALDRICH

99%

别名:

全氟溴辛烷, 全氟辛基溴

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关于此项目

线性分子式:

CF₃(CF₂)₇Br

化学文摘社编号:

423-55-2

分子量:

498.96

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24861212

EC Number:

207-028-4

Beilstein/REAXYS Number:

2016022

MDL number:

MFCD00042082

Assay:

99%

Form:

liquid

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属性

Quality Level

100

assay

99%

form

liquid

refractive index

n20/D 1.305 (lit.)

bp

142 °C (lit.)

density

1.93 g/mL at 25 °C (lit.)

functional group

bromo, fluoro

SMILES string

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br

InChI

1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26

InChI key

WTWWXOGTJWMJHI-UHFFFAOYSA-N

说明

General description

1-溴十七氟辛烷（全氟辛基溴）是一种全氟化碳。使用精氨酸-甘氨酸-天冬氨酸 (RGD) 多肽对全氟辛基溴的聚乙二醇化聚酯纳米胶囊进行表面修饰，用于肿瘤成像。全氟辛基溴纳米胶囊已被开发作为超声和磁共振成像 (MRI) 的双重造影剂。

Application

1-溴十七氟辛烷（全氟辛基溴）可作为氟-19 磁共振成像血管系统造影剂或用于合成氧载体。它也被用作血液替代品乳剂中的氧载体。

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Detection of fluorine labeled herceptin using cellular (19)F MRI ex vivo.

Dorota Bartusik et al.

Journal of pharmaceutical and biomedical analysis, 51(4), 894-900 (2009-11-10)

The aim of this study was to assess the herceptin efficacy in ex vivo cultures of MCF-7 breast carcinoma cells. Herceptin was used with perfluorooctyl bromide (PFOB) and conjugated with lipoplex, containing plasmid DNA and lipofectamine (LipA), to allow fluorine-19

RGD decoration of PEGylated polyester nanocapsules of perfluorooctyl bromide for tumor imaging: influence of pre or post-functionalization on capsule morphology.

Odile Diou et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 87(1), 170-177 (2013-12-18)

PEGylated polyester nanocapsules of perfluorooctyl bromide (PFOB) were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide by either pre-functionalization or post-functionalization strategies using carbodiimide-assisted chemistry. Both strategies allowed successful linkage of RGD at the surface of nanocapsules with up to 600-950

Nanocapsules of perfluorooctyl bromide for theranostics: from formulation to in vivo targeting.

Diou O, et al.

SPIE Proc., 8955 (2014)

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全球贸易项目编号

货号	GTIN
343862-5G	04061837072925