441511
N-乙酰基-L-亮氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
N-Acetyl-L-(-)-leucine, Acetylleucine
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NHCOCH3)CO2H
化学文摘社编号:
分子量:
173.21
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-706-3
MDL number:
Beilstein/REAXYS Number:
1724849
产品名称
N-乙酰基-L-亮氨酸, ReagentPlus®, 99%
InChI key
WXNXCEHXYPACJF-ZETCQYMHSA-N
InChI
1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1
SMILES string
CC(C)C[C@H](NC(C)=O)C(O)=O
product line
ReagentPlus®
assay
99%
form
solid
optical activity
[α]25/D −23±3°, c = 2 in ethanol
reaction suitability
reaction type: C-H Activation, reaction type: solution phase peptide synthesis, reagent type: catalyst
reaction type: Peptide Synthesis
mp
187-190 °C (lit.)
application(s)
peptide synthesis
functional group
amine, carboxylic acid
Quality Level
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Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Three-dimensional solid-state NMR experiment that correlates the chemical shift and dipolar coupling frequencies of two heteronuclei.
A Ramamoorthy et al.
Journal of magnetic resonance. Series B, 107(1), 88-90 (1995-04-01)
Silke Dorner et al.
Nucleic acids research, 33(9), 3065-3071 (2005-05-27)
The ribosome is a large RNP complex but its main enzymatic activity, the peptidyl transferase, is a ribozyme. As many RNA enzymes use divalent metal ions in catalysis, one of the hypotheses put forward proposed that metal ions might aid
Alexander A Nevzorov et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 164(1), 182-186 (2003-08-23)
A pulse sequence for high resolution separated local field spectroscopy based on "magic sandwich" elements is demonstrated on a single crystal sample. Simulations and experimental results show that this pulse sequence has a reduced frequency offset dependence compared to PISEMA
C Ferber-Viart et al.
Audiology & neuro-otology, 14(1), 17-25 (2008-07-30)
For 40 years, the amino acid acetyl-DL-leucine (or isoleucine - Tanganil) has been used in clinical practice to reduce imbalance and autonomic manifestations associated with acute vertigo crises. In animal models, acetyl-DL-leucine accelerates vestibular compensation following unilateral labyrinthectomy, and has
Gilles Clément et al.
Journal of vestibular research : equilibrium & orientation, 17(5-6), 227-237 (2008-07-16)
Pitch head-and-trunk movements during constant velocity rotation are a provocative vestibular stimulus that produces vertigo and nausea. When exposed to this stimulus repeatedly, motion sickness symptoms diminish as the subjects habituate. Acetylleucine is a drug that is used to treat
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