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445460

HATU

97%, for peptide synthesis

别名:

1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, N-[(Dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide

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关于此项目

经验公式（希尔记法）:
C10H15F6N6OP
化学文摘社编号:
148893-10-1
分子量:
380.23
UNSPSC Code:
12352302
PubChem Substance ID:
24868183
NACRES:
NA.22
MDL number:
MFCD27957364
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产品名称

HATU, 97%

Quality Level

200

assay

97%

form

solid

reaction suitability

reaction type: Coupling Reactions

mp

183-185 °C (lit.)

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.CN(C)[C+](N(C)C)n1n[n+]([O-])c2ncccc12

InChI

1S/C10H15N6O.F6P/c1-13(2)10(14(3)4)15-8-6-5-7-11-9(8)16(17)12-15;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChI key

FKBFHOSFPRWJNV-UHFFFAOYSA-N

Application

Peptide coupling reagent.
Preparation of N-arylsulfonamide-linked peptides by solid-phase synthesis.
Reagent for:
Synthesis of Aurora A kinase inhibitors
HPLC assay to determine D- and L- acid enantiomers in human plasma
Amide bond formation reactions

Catalyst for:
Selective acylation
Selecocyclization-oxidation deselenation sequence

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1A

supp_hazards

EUH044

存储类别

4.1A - Other explosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKDB5614
MKDB1144
MKDB2089
SDBB8101
MKCZ8318

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商品

gamma Valerolactone Bio Based Dipolar Aprotic Solvent

Explore gamma-valerolactone (GVL) as a greener solvent replacing DMF, NMP, and DMAc in organic synthesis with efficiency and low toxicity.

Yi He et al.
Organic letters, 8(12), 2483-2485 (2006-06-02)
N-Acylsulfonamide safety-catch linkers are versatile tools in solid-phase organic synthesis because of their stability. This stability necessitates linker activation prior to compound cleavage. Here, we demonstrate that the N-acylsulfonamide group can react with a pi-allyl palladium complex and that these
Pept., Proceedings of the European Peptide Symposium., ed. U. Ragnarrson, 27, 272-273 (2002)
J. Prakt. Chem./Chem.-Ztg., 340, 581-583 (1998)
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全球贸易项目编号

货号GTIN
445460-25G04061832283951
445460-5G04061832283968
445460-1G04061832283890
445460-100G04061832283845