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447439

1-甲基- L -色氨酸

Name: 1-甲基-<SC> L </SC>-色氨酸
Brand: ALDRICH

95%, for peptide synthesis

别名:

(S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, L-(-)-1-Methyltryptophan

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₄N₂O₂

化学文摘社编号:

21339-55-9

分子量:

218.25

UNSPSC Code:

12352209

PubChem Substance ID:

24868339

NACRES:

NA.22

MDL number:

MFCD00467133

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属性

产品名称

1-甲基- L -色氨酸, 95%

Quality Level

100

assay

95%

form

solid

optical activity

[α]24/D −8.0°, c = 2 in acetic acid

reaction suitability

reaction type: solution phase peptide synthesis

mp

242-245 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cn1cc(C[C@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1

InChI key

ZADWXFSZEAPBJS-JTQLQIEISA-N

说明

Application

1-甲基-L-色氨酸可用于：

制备L-色氨酸基配体，用于1，2，3-三唑的区域选择性铜催化N²-芳基化。
作为全合成（& # 8722；）-ardeemin的关键开始物料。
在环肽封端的金纳米颗粒的合成中作为药物递送系统。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Development of a L?Tryptophan?Based Ligand for Regioselective Copper Catalyzed N2?Arylation of 1, 2, 3?Triazoles.

Lopes A B, et al.

ChemistrySelect, 2(22), 6544-6548 (2017)

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

Stefanie Siegert et al.

PloS one, 6(11), e27618-e27618 (2011-11-24)

Adaptive immune responses are initiated when T cells encounter antigen on dendritic cells (DC) in T zones of secondary lymphoid organs. T zones contain a 3-dimensional scaffold of fibroblastic reticular cells (FRC) but currently it is unclear how FRC influence

Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

Juliana Croitoru-Lamoury et al.

PloS one, 6(2), e14698-e14698 (2011-03-02)

The kynurenine pathway (KP) of tryptophan metabolism is linked to antimicrobial activity and modulation of immune responses but its role in stem cell biology is unknown. We show that human and mouse mesenchymal and neural stem cells (MSCs and NSCs)

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全球贸易项目编号

货号	GTIN
447439-5G	04061832288581
447439-1G	04061832288574