47619
芴甲氧羰基-O-叔丁基-L-丝氨酸
≥98.0% (HPLC), for peptide synthesis
别名:
Fmoc-O-叔丁基-L-丝氨酸
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关于此项目
经验公式（希尔记法）:
C22H25NO5
CAS Number:
分子量:
383.44
Beilstein:
3632013
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
Product Name
芴甲氧羰基-O-叔丁基-L-丝氨酸, ≥98.0% (HPLC)
质量水平
方案
≥98.0% (HPLC)
表单
powder
旋光性
[α]20/D +25.5±1°, c = 1% in ethyl acetate
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
应用
peptide synthesis
官能团
Fmoc
储存温度
2-8°C
SMILES字符串
CC(C)(C)OC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChI key
REITVGIIZHFVGU-IBGZPJMESA-N
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应用
FMOC-O-叔丁基-L-丝氨酸是用于多肽合成的 N-末端保护试剂。一些已报道的应用实例有：
- 通过化学选择性丝氨酸连接的环化反应，对抗生素达托霉素进行全合成。
- 使用反复五氟苯酯介导的片段缩合制备MUC1，一种T细胞辅助多肽。
- 泛素和双泛素的线性固相多肽合成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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