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47622

Fmoc-Thr(tBu)-OH

Name: Fmoc-Thr(tBu)-OH
Brand: ALDRICH

≥98.0% (HPLC), for peptide synthesis

别名:

Fmoc-O-叔丁基-L-苏氨酸

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关于此项目

经验公式（希尔记法）:

C₂₃H₂₇NO₅

化学文摘社编号:

71989-35-0

分子量:

397.46

NACRES:

NA.26

PubChem Substance ID:

57651042

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

276-261-1

MDL number:

MFCD00077075

Beilstein/REAXYS Number:

4581133

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属性

产品名称

Fmoc-Thr(tBu)-OH, ≥98.0% (HPLC)

Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]20/D +16±1°, c = 1% in ethyl acetate

reaction suitability

reaction type: C-H Activation, reaction type: Fmoc solid-phase peptide synthesis, reagent type: ligand
reaction type: Peptide Synthesis

application(s)

peptide synthesis

functional group

Fmoc, amine, carboxylic acid

storage temp.

2-8°C

SMILES string

C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/t14-,20+/m1/s1

InChI key

LZOLWEQBVPVDPR-VLIAUNLRSA-N

说明

General description

Fmoc-Thr(tBu)-OH也称为Fmoc-O-叔丁基-L-苏氨酸，常用作多肽合成中的氨基酸合成砌块。

Application

Fmoc-Thr(tBu)-OH可用于通过固相多肽合成反应合成chlorofusin类似物。此外，在复杂的缩酚酸肽(depsipeptide)固相合成中，可作为胺和羟基的保护基。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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General Fmoc-Based Solid-Phase Synthesis of Complex Depsipeptides Circumventing Problematic Fmoc Removal

A Lobo-Ruiz

European Journal of Organic Chemistry, 2020, 183-192 (2020)

Solid-phase synthesis of chlorofusin analogues

ECY Woon

The Journal of Organic Chemistry, 72, 5146-5151 (2007)

Complex formation processes and metal ion catalyzed oxidation of model peptides related to the metal binding site of the human prion protein.

Gizella Csire et al.

Journal of inorganic biochemistry, 203, 110927-110927 (2019-12-07)

Interaction of copper(II) and nickel(II) ions with the Ac-PHAAAGTHSMKHM-NH2 tridecapeptide containing the His85, His96 and His111 binding sites of human prion protein has been studied by various techniques. pH-potentiometry, UV-Vis and circular dichroism spectroscopy were applied to study the stoichiometry

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全球贸易项目编号

货号	GTIN
47622-1KG-F	04061826222676
47622-100G-F	04061832362168
47622-25G-F	04061832642550
47622-10G-F	04061832362175
47622-1G-F	04061826222669