47624
Fmoc-Lys(Boc)-OH
≥98.0% (HPLC), for peptide synthesis
别名:
Nα-芴甲氧羰基-Nε-叔丁氧羰基-L-赖氨酸
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关于此项目
经验公式（希尔记法）:
C26H32N2O6
CAS Number:
分子量:
468.54
Beilstein:
4217767
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
Product Name
Fmoc-Lys(Boc)-OH, ≥98.0% (HPLC)
质量水平
方案
≥98.0% (HPLC)
表单
solid
旋光性
[α]20/D −12±1°, c = 1% in DMF
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
应用
peptide synthesis
官能团
Boc
Fmoc
储存温度
2-8°C
SMILES字符串
CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1
InChI key
UMRUUWFGLGNQLI-QFIPXVFZSA-N
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一般描述
Fmoc-Lys(Boc)-OH 是一种氨基酸衍生物，用于Fmoc固相合成多肽的试剂。
应用
Fmoc-Lys（Boc）-OH可用于：
- 通过与对甲基苯甲胺（MBHA）树脂偶联固相合成五取代的二氢咪唑基丁基二氢咪唑-3-盐。
- 基于Fmoc多肽合成线性嵌插剂双萘四酰亚二胺
- 合成ε-Boc-ε-(3,5-双-三氟甲基-苄基)-α-Fmoc-L-赖氨酸，可用作基于19F NMR的筛选工具。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Marine Bacchi et al.
Protein science : a publication of the Protein Society, 25(12), 2225-2242 (2016-09-28)
Synthetic biology (or chemical biology) is a growing field to which the chemical synthesis of proteins, particularly enzymes, makes a fundamental contribution. However, the chemical synthesis of catalytically active proteins (enzymes) remains poorly documented because it is difficult to obtain
Marta Kulik et al.
Biochimie, 138, 32-42 (2017-04-12)
A fragment of 23S ribosomal RNA (nucleotides 1906-1924 in E. coli), termed Helix 69, forms a hairpin that is essential for ribosome function. Helix 69 forms a conformationally flexible inter-subunit connection with helix 44 of 16S ribosomal RNA, and the nucleotide
Improved synthesis of polyfluorinated l-lysine for 19F NMR-based screening.
Malgesini B, et al.
Molecular Diversity, 13(1), 53-56 (2009)
Solid-phase parallel synthesis of substituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts.
Acharya AN, et al.
Tetrahedron Letters, 43(7), 1157-1160 (2002)
Kavita Bansal et al.
Bioconjugate chemistry, 29(4), 1102-1110 (2018-03-01)
Peptide-based drug delivery systems have become a mainstay in the contemporary medicinal field, resulting in the design and development of better pharmaceutical formulations. However, most of the available reports employ tedious multiple reaction steps for the conjugation of bioactive cationic
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