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Merck
CN

47624

Fmoc-Lys(Boc)-OH

≥98.0% (HPLC), for peptide synthesis

别名:

Nα-芴甲氧羰基-Nε-叔丁氧羰基-L-赖氨酸

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关于此项目

经验公式(希尔记法):
C26H32N2O6
化学文摘社编号:
分子量:
468.54
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
276-256-4
MDL number:
Beilstein/REAXYS Number:
4217767
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产品名称

Fmoc-Lys(Boc)-OH, ≥98.0% (HPLC)

InChI key

UMRUUWFGLGNQLI-QFIPXVFZSA-N

InChI

1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1

SMILES string

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

assay

≥98.0% (HPLC)

form

solid

optical activity

[α]20/D −12±1°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Boc, Fmoc

storage temp.

2-8°C

Quality Level

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General description

Fmoc-Lys(Boc)-OH 是一种氨基酸衍生物,用于Fmoc固相合成多肽的试剂。

Application

Fmoc-Lys(Boc)-OH可用于:
  • 通过与甲基苯甲胺(MBHA)树脂偶联固相合成五取代的二氢咪唑基丁基二氢咪唑-3-盐。
  • 基于Fmoc多肽合成线性嵌插剂双萘四酰亚二胺
  • 合成ε-Boc-ε-(3,5-双-三氟甲基-苄基)-α-Fmoc-L-赖氨酸,可用作基于19F NMR的筛选工具。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bioconjugate chemistry, 29(4), 1102-1110 (2018-03-01)
Peptide-based drug delivery systems have become a mainstay in the contemporary medicinal field, resulting in the design and development of better pharmaceutical formulations. However, most of the available reports employ tedious multiple reaction steps for the conjugation of bioactive cationic

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