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关于此项目
经验公式(希尔记法):
C26H32N2O6
化学文摘社编号:
分子量:
468.54
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
276-256-4
MDL number:
Beilstein/REAXYS Number:
4217767
产品名称
Fmoc-Lys(Boc)-OH, ≥98.0% (HPLC)
InChI key
UMRUUWFGLGNQLI-QFIPXVFZSA-N
InChI
1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1
SMILES string
CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
assay
≥98.0% (HPLC)
form
solid
optical activity
[α]20/D −12±1°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Boc
Fmoc
storage temp.
2-8°C
Quality Level
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Application
Fmoc-Lys(Boc)-OH可用于:
- 通过与对甲基苯甲胺(MBHA)树脂偶联固相合成五取代的二氢咪唑基丁基二氢咪唑-3-盐。
- 基于Fmoc多肽合成线性嵌插剂双萘四酰亚二胺
- 合成ε-Boc-ε-(3,5-双-三氟甲基-苄基)-α-Fmoc-L-赖氨酸,可用作基于19F NMR的筛选工具。
General description
Fmoc-Lys(Boc)-OH 是一种氨基酸衍生物,用于Fmoc固相合成多肽的试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Marine Bacchi et al.
Protein science : a publication of the Protein Society, 25(12), 2225-2242 (2016-09-28)
Synthetic biology (or chemical biology) is a growing field to which the chemical synthesis of proteins, particularly enzymes, makes a fundamental contribution. However, the chemical synthesis of catalytically active proteins (enzymes) remains poorly documented because it is difficult to obtain
Bis-naphthalene diimide exhibiting an effective bis-threading intercalating ability.
Nojima T, et al.
Nucleic Acids Symposium Series, 3(1), 123-124 (2003)
Solid-phase parallel synthesis of substituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts.
Acharya AN, et al.
Tetrahedron Letters, 43(7), 1157-1160 (2002)
Improved synthesis of polyfluorinated l-lysine for 19F NMR-based screening.
Malgesini B, et al.
Molecular Diversity, 13(1), 53-56 (2009)
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