47638
Fmoc-Val-OH
≥98.0% (HPLC)
别名:
N-(9-芴甲氧羰基)-L-缬氨酸, Fmoc-L-缬氨酸
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关于此项目
经验公式（希尔记法）:
C20H21NO4
化学文摘社编号:
分子量:
339.39
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
272-515-0
MDL number:
Beilstein/REAXYS Number:
2177443
Quality Level
assay
≥98.0% (HPLC)
form
solid
optical activity
[α]20/D −17±1°, c = 1% in DMF
reaction suitability
reaction type: C-H Activation, reaction type: Fmoc solid-phase peptide synthesis, reagent type: ligand
reaction type: Peptide Synthesis
mp
143-145 °C (lit.), 143-147 °C
application(s)
peptide synthesis
functional group
Fmoc, amine, carboxylic acid
storage temp.
2-8°C
SMILES string
CC(C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m0/s1
InChI key
UGNIYGNGCNXHTR-SFHVURJKSA-N
General description
Fmoc-Val-OH又称为Fmoc-L-缬氨酸, 在Fmoc固相法多肽合成中起多种作用。
Application
作为起始原料，Fmoc-Val-OH可用于：
- 使用O-酰基异二肽(O-acyl isodipeptide)单元，合成含困难序列的五肽
- 按backbone amide linker(BAL)策略通过Fmoc固相法合成多肽
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
O-Acyl isopeptide method?for the efficient synthesis of difficult sequence-containing peptides: use of `O-acyl isodipeptide unit
Y Sohma
Tetrahedron Letters, 47, 3013-3017 (2006)
Rosanna Capparelli et al.
PloS one, 4(9), e7191-e7191 (2009-09-29)
Temporins are antimicrobial peptides secreted by the granular glands of the European red frog (Rana temporaria). They are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. This study shows that a synthetic temporin B analogue (TB-YK), acquires
Shih-Hurng Loh et al.
Peptides, 126, 170236-170236 (2019-12-25)
The regulation of intracellular pH (pHi) plays a vital role in various cellular functions. We previously demonstrated that three different acid extruders, the Na+-H+ exchanger (NHE), Na+-HCO3- co-transporter (NBC) and H+-linked monocarboxylate transporter (MCT), functioned together in cultured human radial
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 47638-1KG-F | 04061826222775 |
| 47638-50G-F | 04061832362496 |
| 47638-250G-F | 04061832362472 |