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482609

N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-L-亮氨酸

Name: N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-<SC>L</SC>-亮氨酸
Brand: ALDRICH

97%

别名:

([2S,3R]-3-氨基-2-羟基-4-苯基丁酰基)-L-亮氨酸

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关于此项目

线性分子式:

(CH₃)₂CHCH₂CH[NHCOCH(OH)CH(NH₂)CH₂C₆H₅]CO₂H

化学文摘社编号:

58970-76-6

分子量:

308.37

NACRES:

NA.22

PubChem Substance ID:

24871835

UNSPSC Code:

12352209

EC Number:

261-529-2

MDL number:

MFCD00083262

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属性

Quality Level

100

assay

97%

form

powder or crystals

optical activity

[α]20/D −11°, c = 1 in 1 M NaOH

reaction suitability

reaction type: solution phase peptide synthesis

mp

245 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O

InChI

1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1

InChI key

VGGGPCQERPFHOB-RDBSUJKOSA-N

Gene Information

human ... ANPEP(290), DPP4(1803)
mouse ... Rnpep(215615)
rat ... Mme(24590)

说明

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia: the JALSG GML200 Study.

Atsushi Wakita et al.

International journal of hematology, 96(1), 84-93 (2012-05-29)

We conducted a multicenter prospective randomized study to compare a fixed-scheduled induction therapy with a response-oriented individualized induction therapy for elderly patients with acute myeloid leukemia (AML). Newly diagnosed AML patients, aged between 65 and 80, were randomly assigned to

Effects of bestatin on phagocytic cells in cyclophosphamide-treated mice.

Magdalena Lis et al.

Pharmacological reports : PR, 63(6), 1481-1490 (2012-02-24)

The low-molecular weight dipeptide bestatin is a potent inhibitor of aminopeptidase N and has been demonstrated to have antitumor and immunomodulatory effects. The effects of bestatin on interleukin (IL)-1β synthesis and release by peritoneal macrophages stimulated in vitro with lipopolysaccharide

[Determination of ubenimex in human plasma by HPLC-MS/MS].

Zeng Wang et al.

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 43(4), 609-611 (2012-09-25)

To establish a liquid chromatography tandem mass spectrometry method for the determination of ubenimex in human plasma. The essay was conducted with an API 3000 HPLC-MS/MS system consisted of a Ultimate C18 column (50 mm x 4.6 mm, 5 microm).

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货号	GTIN
482609-500MG	04061832594989