49510
L-谷氨酸 γ-苄酯
≥99.0% (T)
别名:
L-谷氨酸-5-苄酯
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关于此项目
线性分子式:
C6H5CH2OCOCH2CH2CH(NH2)COOH
化学文摘社编号:
分子量:
237.25
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-826-1
Beilstein/REAXYS Number:
1885646
MDL number:
Quality Level
assay
≥99.0% (T)
optical activity
[α]20/D +19±2°, c = 1% in acetic acid
reaction suitability
reaction type: solution phase peptide synthesis
mp
181-182 °C (lit.)
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O
InChI
1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
InChI key
BGGHCRNCRWQABU-JTQLQIEISA-N
Application
L-谷氨酸γ-苄基酯通常用于生物应用的聚合物的合成。其中一些例子是：
- 基于聚（乙二醇）和聚（L-谷氨酸γ-苄基）的可生物还原的嵌段共聚物的合成用于细胞内药物递送。
- 用于磁共振成像（MRI）-可见给药系统的可生物降解的聚（L-谷氨酸）-b-聚乳酸的合成。
- 基于聚（L-谷氨酸）的pH值和温度响应性二嵌段共聚物的合成。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Bioreducible block copolymers based on poly (ethylene glycol) and poly (γ-benzyl L-glutamate) for intracellular delivery of camptothecin.
Thambi T, et al.
Bioconjugate Chemistry, 22(10), 1924-1931 (2011)
Novel pH?and Temperature?Responsive Block Copolymers with Tunable pH?Responsive Range.
He C, et al.
Macromolecular Rapid Communications, 29(6), 490-497 (2008)
Micelles Based on Biodegradable Poly (l-glutamic acid)-b-Polylactide with Paramagnetic Gd Ions Chelated to the Shell Layer as a Potential Nanoscale MRI? Visible Delivery System.
Zhang G, et al.
Biomacromolecules, 9(1), 36-42 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 49510-5G | 04061832415505 |
| 49510-25G | 04061832642635 |