49560
L-谷氨酸二甲酯 盐酸盐
≥99.0% (anhydrous basis material, AT)
别名:
L-Glu(OMe)OMe·HCl
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关于此项目
线性分子式:
CH3COOCH2CH2CH(NH2)COOCH3 · HCl
化学文摘社编号:
分子量:
211.64
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
245-461-0
Beilstein/REAXYS Number:
4238829
MDL number:
产品名称
L-谷氨酸二甲酯 盐酸盐, ≥99.0% (anhydrous basis material, AT)
InChI key
MFUPLHQOVIUESQ-JEDNCBNOSA-N
InChI
1S/C7H13NO4.ClH/c1-11-6(9)4-3-5(8)7(10)12-2;/h5H,3-4,8H2,1-2H3;1H/t5-;/m0./s1
SMILES string
Cl.COC(=O)CC[C@H](N)C(=O)OC
assay
≥99.0% (anhydrous basis material, AT)
optical activity
[α]20/D +26.0±1°, c = 5% in H2O
reaction suitability
reaction type: solution phase peptide synthesis
impurities
~2% water
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J Cancelas et al.
International journal of molecular medicine, 8(5), 531-532 (2001-10-18)
The dimethyl ester of L-glutamic acid (DMG) stimulates insulin release and was proposed as a possible insulinotropic tool in the treatment of non-insulin-dependent diabetes. In such a perspective, it was investigated whether DMG enhances the B-cell secretory response to GLP-1
M Joëls et al.
Experimental brain research, 54(3), 455-462 (1984-01-01)
Electrical stimulation of fimbria-fornix (fi-fx) fibers monosynaptically activated many of the neurons tested in the lateral septal complex (LSC) of the rat. The orthodromically activated LSC neurons were classified as "strongly" orthodromically activated (SOA) or "weakly" orthodromically activated ( WOA
T M Zhang et al.
The American journal of physiology, 270(5 Pt 1), G852-G859 (1996-05-01)
The dimethyl esters of succinic acid (SAD) and glutamic acid (GME) were found to be efficiently metabolized in colon carcinoma cells of the Caco-2 line. The rate of [1,4-14C]SAD and [2,3-14C]SAD conversion to radioactive acidic metabolites, CO2, amino acids, pyruvic
Kazuhiro Eto et al.
American journal of physiology. Endocrinology and metabolism, 285(2), E262-E271 (2003-03-20)
We studied acute changes of secretory vesicle pH in pancreatic beta-cells with a fluorescent pH indicator, lysosensor green DND-189. Fluorescence was decreased by 0.66 +/- 0.10% at 149 +/- 16 s with 22.2 mM glucose stimulation, indicating that vesicular pH
D Bosco et al.
The American journal of physiology, 268(3 Pt 1), C611-C618 (1995-03-01)
We used a hemolytic plaque assay for insulin to determine whether the same pancreatic B cells respond to D-glucose, 2-amino-bicyclo[2,2,1]heptane-2-carboxylic acid (BCH) and the association of this nonmetabolized analogue of L-leucine with either the monomethyl ester of succinic acid (SME)
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