Quality Level
assay
97%
reaction suitability
reaction type: click chemistry
refractive index
n20/D 1.36 (lit.)
bp
153 °C (lit.)
density
1.723 g/mL at 25 °C (lit.)
functional group
carboxylic acid, fluoro
SMILES string
OC(=O)C(F)(F)S(F)(=O)=O
InChI
1S/C2HF3O4S/c3-2(4,1(6)7)10(5,8)9/h(H,6,7)
InChI key
VYDQUABHDFWIIX-UHFFFAOYSA-N
General description
2,2-二氟-2-（氟磺酰基）乙酸试剂可用作酚羟基二氟甲基化的二氟卡宾来源。
Application
2,2-二氟-2-（氟磺酰基）乙酸可被用于以下过程：
- 通过与相应的2-氯吡啶反应制备1-二氟甲基-2-氧代-1,2-二氢吡啶类似物。
- 制备作为新型高效二氟碳试剂的氟磺酰二氟乙酸硅酯用于烯烃的环丙烷化反应。
- 末端烯烃和炔烃与碘二氟甲烷磺酰胺的区域和立体选择性自由基氟烷基化反应。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Skin Corr. 1A
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides.
Zhu JM, et al.
Science China: Chemistry, 54(1), 95-102 (2011)
Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides
Zhu, J. M.; et al.
Science China: Chemistry, 54, 95-102 (2011)
Trimethylsilyl fluorosulfonyldifluoroacetate (TFDA): a new, highly efficient difluorocarbene reagent
Dolbier, William R.; et al.
Journal of Fluorine Chemistry, 125, 459-469 (2004)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 531413-25G | 04061837255540 |