Merck
CN

56485

Sigma-Aldrich

N-羟基硫代琥珀酰亚胺 钠盐

≥98% (HPLC)

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别名:
磺基-NHS, 羟基-2,5-二氧代吡咯烷-3-磺酸 钠盐
经验公式(希尔记法):
C4H4NNaO6S
分子量:
217.13
Beilstein:
6359129
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥98% (HPLC)

形式

powder

组成

carbon, 21.57-22.68 (anhydrous)
nitrogen, 6.28-6.61 (anhydrous)

反应适用性

reaction type: Addition Reactions

杂质

≤4% water

应用

peptide synthesis

SMILES字符串

[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O

InChI

1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

InChI key

RPENMORRBUTCPR-UHFFFAOYSA-M

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应用

N-羟基磺基琥珀酰亚胺钠盐是N-羟基琥珀酰亚胺的一种水溶性磺化类似物。它可以在碳二亚胺如1-乙基-3-(3-二甲基氨基丙基)碳二亚胺(EDC)存在时与羧酸发生偶联反应,形成亲水性的N-羟基磺基琥珀酰亚胺活性酯。这些酯可用于蛋白的交联实验。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

磺基-NHS可用于制备亲水性活性酯,如用于交联剂

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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