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Merck
CN

64430

DL-蛋氨酸亚砜

≥98.5% (NT)

别名:

dl-Methionine sulfoxide

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关于此项目

线性分子式:
CH3SOCH2CH2CH(NH2)COOH
化学文摘社编号:
分子量:
165.21
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
263-700-7
Beilstein/REAXYS Number:
1723793
MDL number:
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InChI key

QEFRNWWLZKMPFJ-UHFFFAOYSA-N

InChI

1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

SMILES string

CS(=O)CCC(N)C(O)=O

assay

≥98.5% (NT)

reaction suitability

reaction type: solution phase peptide synthesis

mp

~240 °C (dec.)

application(s)

peptide synthesis

Quality Level

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General description

DL-蛋氨酸亚砜是DL-蛋氨酸的氧化产物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The replaceability of dl-methionine in the diet of the albino rat with dl-methionine sulfone and dl-methionine methylsulfonium chloride.
Bennet AM, et al.
The Journal of Biological Chemistry, 141(4), 573-578 (1941)
Paul J Beisswenger et al.
Diabetes technology & therapeutics, 14(3), 285-292 (2011-10-26)
Advanced glycation end products (AGEs) and oxidation products (OPs) play an important role in diabetes complications, aging, and damage from sun exposure. Measurement of skin autofluorescence (SAF) has been promoted as a noninvasive technique to measure skin AGEs, but the
Alison M Day et al.
Molecular cell, 45(3), 398-408 (2012-01-17)
Eukaryotic 2-Cys peroxiredoxins (Prx) are abundant antioxidant enzymes whose thioredoxin peroxidase activity plays an important role in protecting against oxidative stress, aging, and cancer. Paradoxically, this thioredoxin peroxidase activity is highly sensitive to inactivation by peroxide-induced Prx hyperoxidation. However, any
John M Ringman et al.
Dementia and geriatric cognitive disorders, 33(4), 219-225 (2012-05-16)
Convergent evidence suggests that oxidative stress plays a central role in the pathology of Alzheimer's disease (AD). We asked if consequently, oxidation of methionine residues to methionine sulfoxide (MetO) was increased in plasma proteins of persons carrying familial AD (FAD)
Roberta Seraglia et al.
Journal of mass spectrometry : JMS, 48(1), 105-110 (2013-01-11)
Increased oxidation of low density lipoprotein (LDL) is characteristic of atherosclerosis. In this frame, high density lipoproteins (HDL) play an important role, being able to remove lipid peroxides (LPOs) and cholesterol from oxidized LDL, so exhibiting a protective role against

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