670820
Pam3-Cys-OH
≥98.0% (TLC), for peptide synthesis
别名:
N-α-棕榈酰-S-[2,3-双(棕榈酰氧基)-(2RS)-丙基]-L-半胱氨酸, 棕榈酰-Cys((RS)-2,3-二(棕榈酰氧基)-丙基)-OH
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关于此项目
经验公式（希尔记法）:
C54H103NO7S
化学文摘社编号:
分子量:
910.46
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
产品名称
Pam3-Cys-OH, ≥98.0% (TLC)
质量水平
方案
≥98.0% (TLC)
反应适用性
reaction type: solution phase peptide synthesis
应用
peptide synthesis
SMILES字符串
CCCCCCCCCCCCCCCC(=O)N[C@@H](CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(O)=O
InChI
1S/C54H103NO7S/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-51(56)55-50(54(59)60)48-63-47-49(62-53(58)45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)46-61-52(57)44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h49-50H,4-48H2,1-3H3,(H,55,56)(H,59,60)/t49?,50-/m0/s1
InChI key
PZFZLRNAOHUQPH-GOOVXGPGSA-N
一般描述
Pam3-Cys-OH是一种在C端含有半胱氨酸残基的脂肽，常用于固相肽合成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Nishi Shakya et al.
Peptides, 32(10), 2131-2133 (2011-10-01)
Prophylactic potential of synthetic bacterial lipopeptide and a TLR2 agonist, Pam3Cys was first evaluated against experimental visceral leishmaniasis in rodent model. After establishing the potential its effect on therapeutic efficacy of miltefosine was also studied. Pam3Cys showed 74.64% inhibition in
Leo L Chan et al.
Journal of immunological methods, 377(1-2), 8-14 (2012-01-24)
Cell proliferation is an important assay for pharmaceutical and biomedical research to test the effects of a variety of treatments on cultured primary cells or cell lines. For immunological studies, the ability to perform rapid cell proliferation analysis allows the
Benny K W Cheung et al.
BMC immunology, 10, 64-64 (2009-12-19)
Mycobacterium tuberculosis (MTB) is a major cause of morbidity and mortality in the world. To combat against this pathogen, immune cells release cytokines including tumor necrosis factor-alpha (TNF-alpha), which is pivotal in the development of protective granulomas. Our previous results
Lipoconjugates for the noncovalent generation of microarrays in biochemical and cellular assays
A Hoff, et al.
Chembiochem, 3, 1183-1191 (2002)
Peter M Moyle et al.
Current medicinal chemistry, 15(5), 506-516 (2008-02-22)
Despite the important role of adjuvants for vaccine development, relatively few adjuvants have been successfully incorporated into vaccines intended for human administration. This is in part due to the high toxicity associated with many experimental adjuvants. This lack of choice
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