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Merck
CN

746614

Sigma-Aldrich

SAM Formation reagent for carboxylic acid terminated monolayer on gold surface

别名:

Carboxylic acid-SAM

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UNSPSC代码:
12352103
NACRES:
NA.23
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一般描述

Carboxylic acid- SAM is an acid terminated self-assembled monolayer on the surface of gold, which is mainly utilized to immobilize the surface atoms. The SAM film formed has a high degree of molecular orientation. This reagent is majorly utilized in surface science, biomineralization, and sensor based applications.

应用

Used to prepare carboxylic acid- terminated self-assembled monolayers (SAMs) on gold surfaces as biosensors detected by QCM (Quartz Crystal Microbalance), SPR (Surface Plasmon Resonance), and electrochemical analysis.
Coupled with carboxyl group activation method using NHS/WSC, carboxylic acid-SAM can be used as an interface to immobilize proteins or peptides and other ligands on gold surfaces.
This SAM Formation Reagent presents less non-specific binding than those commonly prepared with carboxylic acid-SAM.
Storage: Keep tightly closed; packed under Nitrogen gas; store in cooler (0~5 °C); dark and dry place.

象形图

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Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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J Christopher Ball et al.
Analytical chemistry, 75(24), 6932-6937 (2003-12-13)
The enzyme beta-galactosidase has been covalently immobilized onto a gold-coated magnetoelastic film via a self-assembled monolayer (SAM) of omega-carboxylic acid alkylthiol. Use of magnetoelastic transduction allows for the wireless monitoring of enzymatic activity through the associated change in the frequency
Preparation, modification, and crystallinity of aliphatic and aromatic carboxylic acid terminated self-assembled monolayers.
Arnold R, et al.
Langmuir, 18(10), 3980-3992 (2002)
Influence of gold substrate topography on the voltammetry of cytochrome c adsorbed on carboxylic acid terminated self-assembled monolayers.
Leopold MC and Bowden EF
Langmuir, 18(6), 2239-2245 (2002)
Effects of self-assembled monolayers on amperometric glucose biosensors based on an organic-inorganic hybrid system
Wang, Huihui;
Sensors and Actuators B, Chemical, 168, 249-255 (2012)

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