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经验公式(希尔记法):
C4H12Cl2O2PtS2
化学文摘社编号:
分子量:
422.25
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
MDL number:
产品名称
顺-二氯双(二甲基亚砜)铂(II), 97%
SMILES string
Cl[Pt]Cl.CS(C)=O.CS(C)=O
InChI
1S/2C2H6OS.2ClH.Pt/c2*1-4(2)3;;;/h2*1-2H3;2*1H;/q;;;;+2/p-2
InChI key
KDADQDWVKZJTDQ-UHFFFAOYSA-L
assay
97%
form
solid
reaction suitability
core: platinum, reagent type: catalyst
mp
218-224 °C
Quality Level
General description
顺式二氯双(二甲基硫亚砜)合铂(II)是一种钯复合物,可用作多种化学反应的催化剂,包括多氟芳基亚胺的甲基化和甲烷氧化。它是一种有效的C-F 活化预催化剂(precatalyst)。
Application
顺式二氯双(二甲基硫亚砜)合铂(II)可用作:
- 发烟硫酸介导的(SO3-H2SO4)甲烷氧化形成硫酸甲酯(MBS)的催化剂。
- 环金属复合物合成的前体。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
H Nakagawa et al.
Journal of neuro-oncology, 16(1), 69-76 (1993-04-01)
Parenchymal brain tumors, which were metastases of primary lung cancer, were surgically removed from 25 patients. During the operation, patients were administered (intravenous or intracarotid) 100 mg/sq m of cis-diamminedichloroplatinum (CDDP) and postoperatively, they received intravenous CDDP at 3-month intervals
A W Konings et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 9(4), 553-562 (1993-07-01)
cDDP-resistant Ehrlich ascites tumour (EAT) cells (ER cells) were tested for cellular content of total glutathione, heat sensitivity, cDDP sensitivity and synergistic effects of a combined treatment of heat and chemotherapy. In comparison with the non-resistant EAT cells (EN) the
R S Dewoskin et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 9(4), 529-537 (1993-07-01)
The effects of hyperthermia (HY) on cisplatin (CDDP) nephrotoxicity and kidney metal concentrations were evaluated in female F344 rats. Rats were anaesthetized with a xylazine/ketamine mixture, heated on a water-bed for 1 h to an intraperitoneal temperature of 41.1 +/-
Osteosarcoma in adolescents and young adults: new developments and controversies. Thermal chemosensitization of cDDP-resistant cells.
A W Konings et al.
Cancer treatment and research, 62, 93-100 (1993-01-01)
L Türkeri et al.
International urology and nephrology, 25(3), 259-263 (1993-01-01)
Traditional approaches for the treatment of locally advanced bladder tumours may not be sufficient enough. Neoadjuvant chemotherapy, a new modality, may be beneficial by enhancing the local and systemic control of the disease. The background of this new modality and
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