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Merck
CN

77386

2-溴-1-乙基吡啶四氟硼酸盐

≥97.0% (T)

别名:

BEP

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经验公式(希尔记法):
C7H9BBrF4N
化学文摘社编号:
分子量:
273.86
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-900-2
Beilstein/REAXYS Number:
4059265
MDL number:
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产品名称

2-溴-1-乙基吡啶四氟硼酸盐, ≥97.0% (T)

InChI key

YJDXVQLBIAJTHP-UHFFFAOYSA-N

InChI

1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1

SMILES string

F[B-](F)(F)F.CC[n+]1ccccc1Br

assay

≥97.0% (T)

form

crystals

reaction suitability

reaction type: Coupling Reactions

mp

103-107 °C

application(s)

peptide synthesis

functional group

bromo

Quality Level

Other Notes

用于肽合成的偶联试剂;与其他试剂如 BOP、PyBrOP、PyClU、BTFFH、CMBI 相比,外消旋作用更低、反应更快

Application

2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
  • The synthesis of N-methylated peptides in solution and solid phase.
  • The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.

General description

2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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