77386
2-溴-1-乙基吡啶四氟硼酸盐
≥97.0% (T)
别名:
BEP
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关于此项目
经验公式（希尔记法）:
C7H9BBrF4N
化学文摘社编号:
分子量:
273.86
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-900-2
Beilstein/REAXYS Number:
4059265
MDL number:
Quality Segment
assay
≥97.0% (T)
form
crystals
reaction suitability
reaction type: Coupling Reactions
mp
103-107 °C
application(s)
peptide synthesis
functional group
bromo
SMILES string
F[B-](F)(F)F.CC[n+]1ccccc1Br
InChI
1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1
InChI key
YJDXVQLBIAJTHP-UHFFFAOYSA-N
General description
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
Application
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
Other Notes
用于肽合成的偶联试剂；与其他试剂如 BOP、PyBrOP、PyClU、BTFFH、CMBI 相比，外消旋作用更低、反应更快
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)