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Merck
CN

779873

甲基-β-环糊精

Wacker Chemie AG, ≥98.0% cyclodextrin basis

别名:

Cavasol® W7 M Life Science, MβCD

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关于此项目

化学文摘社编号:
128446-36-6
MDL number:
MFCD00066764
UNSPSC Code:
12352201
NACRES:
NA.22

主要文件

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产品名称

甲基-β-环糊精, Wacker Chemie AG, ≥98.0% cyclodextrin basis

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

assay

≥98.0% cyclodextrin basis

form

powder

optical activity

[α]/D 154.0 to 156.0°

mol wt

Mw 1310 g/mol

manufacturer/tradename

Wacker Chemie AG

extent of labeling

1.7-1.9 molar substitution

impurities

≤0.10% unsubstituted cyclodextrin
≤0.20% chloride
≤0.50% reducing substances
≤50 ppm volatile organics

ign. residue

≤0.50%

loss

≤5.0% loss on drying

color

white to off-white

mp

180-182 °C (lit.)

absorption

≤0.10 at 350-600 nm in solution at 10%
≤1.00 at 220-350 nm in solution at 10%

Quality Level

200

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相关类别

Application

甲基-β-环糊精是一种大环化合物，可以与许多客体分子形成包合物。与母体β-环糊精相比，它在水溶液中呈现更高的溶解度以及更强的增溶和络合能力。MβCD可用于增强有机溶剂中的酶活性和枯草杆菌蛋白酶的对映选择性。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。
仅供R&D使用

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

368.6 °F

flash_point_c

187 °C

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN3719
BCCM8982
BCCM8283
BCCM8282
BCCM4323

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Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.
Ribeiro A
Aaps Pharmscitech, 9(4), 1102-1109 (2008)
Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.
Griebenow K
Journal of the American Chemical Society, 121(36), 8157-8163 (1999)
Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
Laurie Hamtiaux et al.
PloS one, 6(10), e26823-e26823 (2011-11-03)
The antitumoral properties of endocannabinoids received a particular attention these last few years. Indeed, these endogenous molecules have been reported to exert cytostatic, apoptotic and antiangiogenic effects in different tumor cell lines and tumor xenografts. Therefore, we investigated the cytotoxicity
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