850993
2-氨基异丁酸
98%, for peptide synthesis
别名:
α-氨基异丁酸, 2-甲基丙氨酸, Aib
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关于此项目
线性分子式:
(CH3)2C(NH2)COOH
化学文摘社编号:
分子量:
103.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
200-544-0
MDL number:
Beilstein/REAXYS Number:
506496
产品名称
2-氨基异丁酸, 98%
SMILES string
CC(C)(N)C(O)=O
InChI
1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
InChI key
FUOOLUPWFVMBKG-UHFFFAOYSA-N
assay
98%
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
mp
≥300 °C
application(s)
peptide synthesis
Quality Level
General description
2-氨基异丁酸又名α-氨基丁酸，是一种氨基酸，用于液相多肽合成法。强烈促进肽形成螺旋，适合作为肽合成构件。
Application
2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代，对C−H提取呈惰性，因而在肽链中掺入这种化合物可避免发生不需要的反应。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Photochemical methods for peptide macrocyclisation
Chemistry?A European Journal , 27, 69-88 (2021)
C Lucarelli et al.
Journal of chromatography, 541(1-2), 285-296 (1991-03-22)
A procedure is described for the determination of alpha-methyldopa (MD) [L-3-(3,4-dihydroxyphenyl)-2-methylalanine], its metabolite and catecholamines in the urine and plasma of patients undergoing MD therapy, by high-performance liquid chromatography with dual working electrode coulometric detection. An efficient sample preparation procedure
Amphiphilic polypeptides with prolonged enzymatic stability for the preparation of self-assembled nanobiomaterials
Royal Society of Chemistry Advances, 8, 34603-34613 (2018)
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
Jamie E Elsila et al.
Astrobiology, 11(2), 123-133 (2011-03-23)
The presence of nonprotein α-dialkyl-amino acids such as α-aminoisobutyric acid (α-AIB) and isovaline (Iva), which are considered to be relatively rare in the terrestrial biosphere, has long been used as an indication of the indigeneity of meteoritic amino acids. However
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