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Merck
CN

850993

Sigma-Aldrich

2-氨基异丁酸

98%, for peptide synthesis

别名:

α-氨基异丁酸, 2-甲基丙氨酸, Aib

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关于此项目

线性分子式:
(CH3)2C(NH2)COOH
化学文摘社编号:
分子量:
103.12
Beilstein:
506496
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22
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产品名称

2-氨基异丁酸, 98%

质量水平

方案

98%

表单

solid

反应适用性

reaction type: solution phase peptide synthesis

mp

≥300 °C

应用

peptide synthesis

SMILES字符串

CC(C)(N)C(O)=O

InChI

1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)

InChI key

FUOOLUPWFVMBKG-UHFFFAOYSA-N

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一般描述

2-氨基异丁酸又名α-氨基丁酸,是一种氨基酸,用于液相多肽合成法。强烈促进肽形成螺旋,适合作为肽合成构件。

应用

2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代,对C−H提取呈惰性,因而在肽链中掺入这种化合物可避免发生不需要的反应。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Photochemical methods for peptide macrocyclisation
Chemistry?A European Journal , 27, 69-88 (2021)
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
C Lucarelli et al.
Journal of chromatography, 541(1-2), 285-296 (1991-03-22)
A procedure is described for the determination of alpha-methyldopa (MD) [L-3-(3,4-dihydroxyphenyl)-2-methylalanine], its metabolite and catecholamines in the urine and plasma of patients undergoing MD therapy, by high-performance liquid chromatography with dual working electrode coulometric detection. An efficient sample preparation procedure
Amphiphilic polypeptides with prolonged enzymatic stability for the preparation of self-assembled nanobiomaterials
Royal Society of Chemistry Advances, 8, 34603-34613 (2018)
Oak Z Chi et al.
Anesthesia and analgesia, 110(5), 1412-1418 (2010-03-23)
We performed experiments to test whether isoflurane pretreatment produces vascular effects, especially at the levels of arterioles and capillaries affecting regional cerebral blood flow (rCBF), O(2) supply and consumption, or capillary permeability in focal cerebral ischemia. Because inducible nitric oxide

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