855642
N-乙酰基-L-谷氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
(2S)-2-Acetamidopentanedioic acid, N-Acetylglutamic acid
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关于此项目
线性分子式:
HO2CCH2CH2CH(NHCOCH3)CO2H
化学文摘社编号:
分子量:
189.17
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-708-4
MDL number:
Beilstein/REAXYS Number:
1727473
产品名称
N-乙酰基-L-谷氨酸, ReagentPlus®, 99%
InChI key
RFMMMVDNIPUKGG-YFKPBYRVSA-N
InChI
1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1
SMILES string
CC(=O)N[C@@H](CCC(O)=O)C(O)=O
product line
ReagentPlus®
assay
99%
form
powder
optical activity
[α]22/D −15.6°, c = 1 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
Quality Level
application(s)
peptide synthesis
storage temp.
2-8°C
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Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Jiguang Wang et al.
Poultry science, 99(7), 3583-3593 (2020-07-04)
The present study determined the effects of in ovo feeding (IOF) of N-acetyl-L-glutamate (NAG) on early intestinal development and growth performance of broilers. A total of 702 fertile broiler eggs were randomly divided into 3 treatments: 1) non-punctured control group
M Tuchman et al.
Pediatric research, 27(4 Pt 1), 408-412 (1990-04-01)
N-acetylglutamate (NAG) content was measured in homogenates of liver and small intestine obtained from normal and 24-h starved syngeneic mice. Subsequently, NAG was determined in normal, and in carbamyl phosphate synthetase I and ornithine transcarbamylase enzyme-deficient human liver tissue homogenates.
W Zhang et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 13(4), 183-188 (1990-08-01)
Liver tissue from 3 patients with carbamyl phosphate synthetase I deficiency and 11 patients with ornithine transcarbamylase deficiency was analyzed by Western blots for the presence of carbamyl phosphate synthetase I and ornithine transcarbamylase cross-reactive material with anti-rat enzyme antibodies.
J Vockley et al.
Biochemical medicine and metabolic biology, 47(1), 38-46 (1992-02-01)
N-Acetyl-L-glutamate synthetase (NAG synthetase) is a mitochondrial matrix enzyme which catalyzes the synthesis of N-acetyl-Lglutamate (NAG), a physiologic activator of the urea cycle enzyme carbamylphosphate synthetase I. Deficiency of NAG synthetase in humans has been reported only three times previously.
Jun Wu et al.
Nature cell biology, 23(1), 75-86 (2021-01-10)
Nutrient availability is central for T-cell functions and immune responses. Here we report that CD8+ T-cell activation and anti-tumour responses are strongly potentiated by the non-essential amino acid Asn. Increased Asn levels enhance CD8+ T-cell activation and effector functions against
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