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855987

D -缬氨酸

Name: <SC>D </SC>-缬氨酸
Brand: ALDRICH

≥98%, for peptide synthesis

别名:

D-α-氨基异戊酸, D-2-氨基-3-甲基丁酸

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关于此项目

线性分子式:

(CH₃)₂CHCH(NH₂)CO₂H

化学文摘社编号:

640-68-6

分子量:

117.15

NACRES:

NA.22

PubChem Substance ID:

24888396

UNSPSC Code:

12352209

EC Number:

211-368-9

MDL number:

MFCD00064219

Beilstein/REAXYS Number:

1721135

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属性

产品名称

D -缬氨酸, ≥98%

Quality Level

100

assay

≥98%

form

powder

optical activity

[α]23/D −32.0 to −24.0°, c = 8 in 6 M HCl

optical purity

ee: 99% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

>295 °C (subl.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)[C@@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1

InChI key

KZSNJWFQEVHDMF-SCSAIBSYSA-N

说明

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.

Kimberly A Smith et al.

American journal of respiratory cell and molecular biology, 53(3), 355-367 (2015-01-09)

Hypoxic pulmonary vasoconstriction (HPV) is an important physiological response that optimizes the ventilation/perfusion ratio. Chronic hypoxia causes vascular remodeling, which is central to the pathogenesis of hypoxia-induced pulmonary hypertension (HPH). We have previously shown that Notch3 is up-regulated in HPH

Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.

Shanshan Song et al.

American journal of physiology. Cell physiology, 307(4), C373-C383 (2014-06-13)

An increase in cytosolic Ca(2+) concentration ([Ca(2+)]cyt) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for pulmonary arterial medial hypertrophy in patients with idiopathic pulmonary arterial hypertension (IPAH). Vascular smooth

Vitamin D reverses aPL-induced inflammation and LMWH-induced sFlt-1 release by human trophoblast.

Stefan M Gysler et al.

American journal of reproductive immunology (New York, N.Y. : 1989), 73(3), 242-250 (2014-07-30)

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment with low molecular weight heparin (LMWH) reduces the risk of RPL but not preeclampsia. Moreover, LMWH

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全球贸易项目编号

货号	GTIN
855987-25G	04061833026175
855987-5G	04061833026489