860794
Z-L-苯丙氨酸氯甲酮
98%
别名:
N-苄氧羰基-L-苯丙氨酰甲基氯酮, ZPCK
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关于此项目
线性分子式:
C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl
化学文摘社编号:
分子量:
331.79
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
247-432-8
MDL number:
产品名称
Z-L-苯丙氨酸氯甲酮, 98%
InChI key
OYHLRJGDELITAF-INIZCTEOSA-N
InChI
1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1
SMILES string
ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2
assay
98%
form
powder
optical activity
[α]23/D +30°, c = 1 in chloroform
reaction suitability
reaction type: solution phase peptide synthesis
mp
107-108 °C (lit.)
application(s)
peptide synthesis
storage temp.
−20°C
Quality Level
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Application
酶抑制剂。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
G Jung et al.
Protein science : a publication of the Protein Society, 4(11), 2433-2435 (1995-11-01)
The essential histidine residue of carboxypeptidase Y (CPY) was modified by a site-specific reagent, a chloromethylketone derivative of benzyloxycarbonyl-L-phenylalanine. The single modified histidine residue was converted to N tau-carboxy-methyl histidine (cmHis) upon performic acid oxidation. A peptide containing cmHis was
L A Johnson et al.
Biochimica et biophysica acta, 953(3), 269-279 (1988-04-14)
The reaction of chymase, a chymotryptic proteinase from human skin, and bovine pancreatic chymotrypsin with a number of time-dependent inhibitors has been studied. An integrated equation, relating product formation with time, has been derived for the reaction of enzymes with
Inhibition of carboxypeptidase Y by chloromethyl ketone derivatives of benzyloxycarbonyl-L-phenylalanine.
R Hayashi et al.
Journal of biochemistry, 76(6), 1355-1357 (1974-12-01)
T Wileman et al.
Cell regulation, 2(9), 753-765 (1991-09-01)
The endoplasmic reticulum, or an organelle closely associated with it, contains proteases that can be used to remove partially assembled or improperly folded proteins. Very little is known at present about the types of protease that degrade these proteins. The
Biogenesis of vaccina: interrelationship between post-translational cleavage, virus assembly, and maturation.
M Silver et al.
Virology, 117(2), 341-356 (1982-03-01)
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