911690
C5 Lenalidomide
≥95%
别名:
3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC® research
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关于此项目
经验公式（希尔记法）:
C13H13N3O3
化学文摘社编号:
分子量:
259.26
UNSPSC Code:
12352101
NACRES:
NA.22
MDL number:
ligand
C5 Lenalidomide
Quality Segment
assay
≥95%
form
powder
reaction suitability
reagent type: ligand
technique(s)
targeted protein degradation: suitable
storage temp.
2-8°C
SMILES string
NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1
InChI
1S/C13H13N3O3/c14-8-1-2-9-7(5-8)6-16(13(9)19)10-3-4-11(17)15-12(10)18/h1-2,5,10H,3-4,6,14H2,(H,15,17,18)
InChI key
WLUIQUZGNPAKRL-UHFFFAOYSA-N
Application
C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
警示词
Warning
危险代码
Hazard Classifications
Repr. 2 - STOT RE 2
靶器官
Blood
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable