930563
Pomalidomide-PEG2-C2-azide
≥95%
别名:
1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl), 4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
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About This Item
经验公式(希尔记法):
C19H22N6O6
CAS Number:
分子量:
430.41
MDL编号:
UNSPSC代码:
51471602
NACRES:
NA.21
应用
Pomalidomide-PEG2-C2-azide is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Contains an alkyne, allowing for conjugation through click chemistry. A basic building block for development of a protein degrader library.
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
其他说明
Targeted Protein Degradation by Small Molecules
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
警示用语:
Danger
危险声明
危险分类
Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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