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A79809

5-氨基水杨酸

Name: 5-氨基水杨酸
Brand: ALDRICH

95%

别名:

5-AS, 5-氨基-2-羟基苯甲酸, 氨水杨酸

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关于此项目

线性分子式:

H₂NC₆H₃-2-(OH)CO₂H

化学文摘社编号:

89-57-6

分子量:

153.14

UNSPSC Code:

12352106

NACRES:

NA.22

PubChem Substance ID:

24891301

EC Number:

201-919-1

Beilstein/REAXYS Number:

2090421

MDL number:

MFCD00007877

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属性

Quality Level

200

assay

95%

form

powder with small lumps

reaction suitability

reaction type: solution phase peptide synthesis

mp

275-280 °C (dec.) (lit.)

application(s)

detection
peptide synthesis

SMILES string

Nc1ccc(O)c(c1)C(O)=O

InChI

1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

InChI key

KBOPZPXVLCULAV-UHFFFAOYSA-N

Gene Information

human ... ALOX5(240), PPARG(5468), PTGS1(5742), PTGS2(5743)

说明

Application

5-氨基水杨酸是适用于ELISA分析的过氧化物酶底物。这一底物产生可溶性的棕色终产物，可在450nm处通过分光光度法读取。使用3 N NaOH可终止反应并在550 nm处读取结果。

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pictograms

GHS07

signalword

Warning

hcodes

H315,H317,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Once-daily dosing vs. conventional dosing schedule of mesalamine and relapse of quiescent ulcerative colitis: systematic review and meta-analysis.

Alexander C Ford et al.

The American journal of gastroenterology, 106(12), 2070-2077 (2011-09-07)

Maintenance therapy with 5-aminosalicylates (5-ASAs) is recommended in patients with quiescent ulcerative colitis (UC), but compliance rates are low. Once-daily dosing may improve adherence, but impact on the relapse of disease activity is unclear as no previous meta-analysis has studied

Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine.

A Lyakhovich et al.

Alimentary pharmacology & therapeutics, 31(2), 202-209 (2009-11-07)

Mesalazine (mesalamine) (5-ASA) is considered an anti-inflammatory drug for the treatment of inflammatory bowel disease. It is well tolerated by most patients and induces mucosal healing specifically in ulcerative colitis. Besides its anti-inflammatory properties, 5-ASA has been studied for cancer

Phylogenetic analysis of dysbiosis in ulcerative colitis during remission.

Mirjana Rajilić-Stojanović et al.

Inflammatory bowel diseases, 19(3), 481-488 (2013-02-07)

Presence of intestinal microbes is a prerequisite for the development of ulcerative colitis (UC), although deviation of the normal intestinal microbiota composition, dysbiosis, is presumably implicated in the etiology of UC. The fecal microbiota of 30 UC samples obtained from

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全球贸易项目编号

货号	GTIN
A79809-100G	04061833390870
A79809-5G	04061833390887