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Merck
CN

G6600

Sigma-Aldrich

甘氨酸甲酯 盐酸盐

99%, for peptide synthesis

别名:

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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关于此项目

线性分子式:
NH2CH2COOCH3 · HCl
CAS Number:
分子量:
125.55
Beilstein:
3593644
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
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Product Name

甘氨酸甲酯 盐酸盐, 99%

质量水平

方案

99%

表单

powder, crystals or chunks

反应适用性

reaction type: solution phase peptide synthesis

颜色

white

mp

175 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H

InChI key

COQRGFWWJBEXRC-UHFFFAOYSA-N

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一般描述

甘氨酸甲酯盐酸盐又名甲基甘氨酸酯盐酸盐,是一种甘氨酸衍生物,用于制备氨基酸和有机化合物。

应用

甘氨酸甲酯盐酸盐可用于合成以氨基酸酯为侧链的环磷腈类物质。还可在水相中合成多肽,是一种绿色的制肽法。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The investigation of thermosensitive properties of phosphazene derivatives bearing amino acid ester groups
A Uslu
Journal of Molecular Structure, 1136, 90-99 (2017)
D Levy
Biochimica et biophysica acta, 317(2), 473-481 (1973-08-30)
A procedure has been described for the modification of the amino group of glycine methyl ester, and the amino groups of the hormone, insulin, with the reagent p-nitrophenyl-p-chloromercuribenzoate, effecting the introduction of the chloromercuri group at various defined sites in
L K Frankel et al.
Biochemistry, 38(43), 14271-14278 (1999-11-26)
The effects of the modification of carboxylate groups on the manganese-stabilizing protein of photosystem II were investigated. Carboxylate groups (including possibly the C-terminus) on the manganese-stabilizing protein were modified with glycine methyl ester in a reaction facilitated by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The
A green protocol for peptide bond formation in WEB
M Konwar
Tetrahedron Letters, 57, 2283-2285 (2016)
Glycine enolates: the large effect of iminium ion formation on alpha-amino carbon acidity.
A Rios et al.
Journal of the American Chemical Society, 123(32), 7949-7950 (2001-08-09)

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