G6600
甘氨酸甲酯 盐酸盐
99%, for peptide synthesis
别名:
Glycine methyl ester·HCl, Methyl glycinate hydrochloride
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关于此项目
线性分子式:
NH2CH2COOCH3 · HCl
化学文摘社编号:
分子量:
125.55
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
227-139-1
MDL number:
Beilstein/REAXYS Number:
3593644
产品名称
甘氨酸甲酯 盐酸盐, 99%
InChI key
COQRGFWWJBEXRC-UHFFFAOYSA-N
InChI
1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
SMILES string
Cl.COC(=O)CN
assay
99%
form
powder, crystals or chunks
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
175 °C (dec.) (lit.)
application(s)
peptide synthesis
Quality Level
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Application
甘氨酸甲酯盐酸盐可用于合成以氨基酸酯为侧链的环磷腈类物质。还可在水相中合成多肽，是一种绿色的制肽法。
General description
甘氨酸甲酯盐酸盐又名甲基甘氨酸酯盐酸盐，是一种甘氨酸衍生物，用于制备氨基酸和有机化合物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
The investigation of thermosensitive properties of phosphazene derivatives bearing amino acid ester groups
A Uslu
Journal of Molecular Structure, 1136, 90-99 (2017)
A green protocol for peptide bond formation in WEB
M Konwar
Tetrahedron Letters, 57, 2283-2285 (2016)
L K Frankel et al.
Biochemistry, 38(43), 14271-14278 (1999-11-26)
The effects of the modification of carboxylate groups on the manganese-stabilizing protein of photosystem II were investigated. Carboxylate groups (including possibly the C-terminus) on the manganese-stabilizing protein were modified with glycine methyl ester in a reaction facilitated by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The
D Levy
Biochimica et biophysica acta, 317(2), 473-481 (1973-08-30)
A procedure has been described for the modification of the amino group of glycine methyl ester, and the amino groups of the hormone, insulin, with the reagent p-nitrophenyl-p-chloromercuribenzoate, effecting the introduction of the chloromercuri group at various defined sites in
K W Kuo et al.
International journal of peptide and protein research, 46(2), 181-185 (1995-08-01)
To study the functional involvements of the common interaction of the Leu-1 alpha-amino group and Asp-58 in cobrotoxin, the lysine epsilon-amino groups of cobrotoxin were initially guanidinated with o-methylisourea. The alpha-amino group of Leu-1 was them modified with TNBS after
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