H1256
羟苯基丙酸 N-羟基琥珀酰亚胺酯
~90%
别名:
N-[(4-羟基氢化肉桂酰基)氧基]琥珀酰亚胺, N-琥珀酰亚胺 3-(4-羟基苯基)丙酸酯, Bolton-Hunter 试剂前体, Rudinger 试剂, SHPP
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关于此项目
经验公式（希尔记法）:
C13H13NO5
化学文摘社编号:
分子量:
263.25
Beilstein:
1545011
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22
方案
~90%
质量水平
反应适用性
reagent type: linker
mp
132-133 °C (lit.)
应用
peptide synthesis
储存温度
−20°C
SMILES字符串
Oc1ccc(CCC(=O)ON2C(=O)CCC2=O)cc1
InChI
1S/C13H13NO5/c15-10-4-1-9(2-5-10)3-8-13(18)19-14-11(16)6-7-12(14)17/h1-2,4-5,15H,3,6-8H2
InChI key
KYRUKRFVOACELK-UHFFFAOYSA-N
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应用
3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester can be used to prepare 125I-labeled reagents, which are used in binding assay studies of proteins and peptides.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Preparation of 125-I-labeled oligosaccharide derivatives with the aid of 3-(4-hydroxyphenyl) propionic acid N-hydroxysuccinimide ester
Himmelspach K, et al.
Febs Letters, 75(1-2), 154-158 (1977)
Radioimmunoassay of iodinated gentamicin
Broughton, Alan and Strong, James E
Clinica Chimica Acta; International Journal of Clinical Chemistry, 66(1), 125-129 (1976)
Comparative methods for the radiolabeling of peptides.
A E Bolton
Methods in enzymology, 124, 18-29 (1986-01-01)
R H Raja et al.
Analytical biochemistry, 139(1), 168-177 (1984-05-15)
Present procedures to obtain radiolabeled hyaluronic acid derivatives are limited to low-specific-activity isotopes and small amounts of material, and often involve multiple points of chemical modification within the polymer. A synthesis has been developed which affords large quantities of a
M P Merker et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4(12), 3040-3048 (1990-09-01)
To study the biochemical characteristics of endothelium in vivo, we radioiodinated endothelial membrane proteins of the perfused rabbit lung using a water soluble analog of the Bolton-Hunter reagent, 125I-sulfosuccinimidyl (hydroxyphenyl) propionate (125I-s-SHPP). This technique led to a 10-fold increase in
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