H8378
2-羟基-D-谷氨酸 二钠盐
≥95% (GC), cell analysisfor peptide synthesis
别名:
（R）-2-羟基戊二酸, （R）-2-羟基戊二酸二钠
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关于此项目
线性分子式:
C5H6O5Na2
化学文摘社编号:
分子量:
192.08
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Beilstein/REAXYS Number:
5318041
产品名称
2-羟基-D-谷氨酸 二钠盐, ≥95% (GC)
InChI key
DZHFTEDSQFPDPP-HWYNEVGZSA-L
SMILES string
[Na].O[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
assay
≥95% (GC)
form
powder
color
white to off-white
application(s)
cell analysis
peptide synthesis
storage temp.
−20°C
Quality Level
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Application
Dα-羟基戊二酸二钠盐可以用作肽合成中的试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Shan Jin et al.
Nature communications, 14(1), 6638-6638 (2023-10-21)
Mammalian lactate dehydrogenase D (LDHD) catalyzes the oxidation of D-lactate to pyruvate. LDHD mutations identified in patients with D-lactic acidosis lead to deficient LDHD activity. Here, we perform a systematic biochemical study of mouse LDHD (mLDHD) and determine the crystal
The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells.
Liu Y, Gilbert MR, Kyprianou N, et al.
Acta Neuropathologica, 128(5), 723-732 (2014)
M Hans et al.
European journal of biochemistry, 265(1), 404-414 (1999-09-22)
Component D (HgdAB) of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum was purified to homogeneity. It is able to use component A from Acidaminococcus fermentans (HgdC) to initiate catalysis together with ATP, Mg2+ and a strong reducing agent such as Ti(III)citrate. Component
Postoperative risk of IDH mutant glioma-associated seizures and their potential management with IDH mutant inhibitors.
Drumm, et al.
The Journal of Clinical Investigation (2023)
Yinghao Liu et al.
Cell reports, 42(2), 112067-112067 (2023-02-02)
The generation of neurons from quiescent radial-glia-like neural stem cells (RGLs) in adult brain goes hand in hand with the modulation of cellular metabolism. However, it is still unclear how the exact metabolic program governs the balance between quiescent and
实验方案
We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.
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