I9760
碘乙酸 N-羟基琥珀酰亚胺酯
for peptide synthesis
别名:
N-碘乙氧基琥珀酰亚胺, N-羟基琥珀酰亚胺碘乙酸
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关于此项目
经验公式（希尔记法）:
C6H6INO4
化学文摘社编号:
分子量:
283.02
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22
MDL number:
产品名称
碘乙酸 N-羟基琥珀酰亚胺酯, powder
form
powder
Quality Level
reaction suitability
reagent type: cross-linking reagent
solubility
DMF: 50 mg/mL
application(s)
peptide synthesis
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(N1OC(CI)=O)CCC1=O
InChI
1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
InChI key
VRDGQQTWSGDXCU-UHFFFAOYSA-N
Application
具有氨基和巯基反应性的双异官能团交联剂。典型情况下，最初通过 pH 7.5 (6.5-8.5) 缓冲条件下的酰胺键偶联到含有伯胺的分子上，接着通过 pH 7.5 (7.0-8.0) 缓冲条件下的硫醚链与含有自由巯基的分子进行特异性次级键合。用于制备酶免疫交联剂和半抗原载体分子偶联物。提供两个原子的连接基。
Disclaimer
碘乙酰基具有光敏性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Cody M Palumbo et al.
Chembiochem : a European journal of chemical biology, 21(11), 1633-1640 (2020-01-17)
Specific applications of CRISPR/Cas genome editing systems benefit from chemical modifications of the sgRNA. Herein we describe a versatile and efficient strategy for functionalization of the 3'-end of a sgRNA. An exemplary collection of six chemically modified sgRNAs was prepared
Kevin Y Lin et al.
ACS nano, 7(10), 9001-9009 (2013-09-11)
Thrombin is a serine protease and regulator of hemostasis that plays a critical role in the formation of obstructive blood clots, or thrombosis, that is a life-threatening condition associated with numerous diseases such as atherosclerosis and stroke. To detect thrombi
G Houen et al.
Journal of immunological methods, 181(2), 187-200 (1995-04-26)
Two methods for the preactivation of proteins and conjugation of peptides to proteins under mild conditions are presented. Preactivation of proteins with divinylsulfone (DVS) permits peptide conjugation through either amino, hydroxyl or sulphydryl groups depending on the coupling pH used
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I9760-50MG | 04061833285060 |
| I9760-100MG | 04061833285053 |