P45850
哌啶甲酸
98%, for peptide synthesis
别名:
(±)-哌啶-2-羧酸, 2-哌啶甲酸, 哌啶甲酸游离碱, 高脯氨酸
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关于此项目
经验公式（希尔记法）:
C6H11NO2
化学文摘社编号:
分子量:
129.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
208-616-3
MDL number:
Beilstein/REAXYS Number:
81095
产品名称
哌啶甲酸, 98%
InChI
1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)
InChI key
HXEACLLIILLPRG-UHFFFAOYSA-N
SMILES string
OC(=O)C1CCCCN1
assay
98%
form
powder and chunks
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
LC/MS: suitable
color
white to beige
mp
282 °C (dec.) (lit.)
Quality Level
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General description
派可林酸又名2-哌啶甲酸，是一种多功能试剂，用于液相多肽合成法。通常用作许多拟肽合成中的脯氨酸替代物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D M Danks et al.
The Journal of pediatrics, 86(3), 382-387 (1975-03-01)
Studies of eight patients with this syndrome confirm the characteristic pattern of abnormalities and the autosomal recessive mode of inheritance. The incidence is estimated to be approximately 1 in 100,000 live births. The liver lesion proved to be variable, with
Conformational heterogeneity about pipecolic acid peptide bonds: conformational, thermodynamic, and kinetic aspects
WJ Wu
The Journal of Organic Chemistry, 63, 6689-6698 (1998)
B T Poll-The et al.
Journal of inherited metabolic disease, 9(2), 169-174 (1986-01-01)
Infantile Refsum's disease was diagnosed in three male patients, presenting with facial dysmorphia, retinitis pigmentosa, neurosensory hearing loss, hepatomegaly, osteopenia and delayed growth and psychomotor development. An elevated plasma phytanic acid concentration and a deficient phytanic acid oxidase activity in
B Plecko et al.
Annals of neurology, 48(1), 121-125 (2000-07-14)
Diagnosis of pyridoxine-dependent epilepsy is based on the clinical response to high-dosage application of pyridoxine. Here, we report on 2 patients with pyridoxine-dependent epilepsy with significant elevation of pipecolic acid concentrations in plasma and cerebrospinal fluid (CSF) and further increase
Isabelle M Medana et al.
The Journal of infectious diseases, 185(5), 650-656 (2002-02-28)
A retrospective study of 261 Vietnamese adults with severe malaria was conducted to determine the relationship between cerebrospinal fluid (CSF) levels of metabolites of the kynurenine pathway, the incidence of neurologic complications, and the disease outcome. Three metabolites were measured:
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