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Merck
CN

W297070

丙酮酸

greener alternative

natural, ≥95%, FG

别名:

α-酮丙酸, 2-氧代戊二酸

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关于此项目

线性分子式:
CH3COCOOH
化学文摘社编号:
分子量:
88.06
FEMA Number:
2970
Council of Europe no.:
19c
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
8.019
EC Number:
204-824-3
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
506211
Organoleptic:
caramel; acidic; sour
Grade:
FG
Halal
Kosher
natural
Food allergen:
no known allergens
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产品名称

丙酮酸, natural, ≥95%, FG

SMILES string

CC(=O)C(O)=O

InChI

1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)

InChI key

LCTONWCANYUPML-UHFFFAOYSA-N

grade

FG
Halal
Kosher
natural

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.515

assay

≥95%

greener alternative product characteristics

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.428 (lit.)

bp

165 °C (lit.)

mp

11-12 °C (lit.)

density

1.267 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

greener alternative category

organoleptic

caramel; acidic; sour

Quality Level

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Application


  • 通过苹果酸酶生物催化和CO2固定高效合成L-苹果酸。:研究重点介绍了由丙酮酸生物催化合成L-苹果酸,展示了一种高效的CO2固定过程。该研究为使用丙酮酸作为前体的可持续化学生产开辟了新途径(Shi et al., 2024)。

  • H(2)S驱动的纳米马达通过诱导铁死亡和乳酸-丙酮酸轴紊乱来主动治疗肿瘤。:研究展示了使用硫化氢驱动的纳米马达进行肿瘤治疗,诱导铁死亡并破坏乳酸-丙酮酸代谢轴,展示了丙酮酸代谢在癌症治疗中的创新应用(Wang et al., 2024)。

Biochem/physiol Actions

5 ppm时具有味觉

General description

天然存在: 芦笋、牛肉、清酒、弗吉尼亚烟草、小麦面包。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

183.2 °F - closed cup

flash_point_c

84 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Robert A Jacobs et al.
American journal of physiology. Endocrinology and metabolism, 304(7), E686-E694 (2013-02-07)
Lactate is an important intermediate metabolite in human bioenergetics and is oxidized in many different tissues including the heart, brain, kidney, adipose tissue, liver, and skeletal muscle. The mechanism(s) explaining the metabolism of lactate in these tissues, however, remains unclear.
Albert P Chen et al.
PloS one, 8(2), e56551-e56551 (2013-02-21)
Following radiation therapy (RT), tumor morphology may remain unchanged for days and sometimes weeks, rendering anatomical imaging methods inadequate for early detection of therapeutic response. Changes in the hyperpolarized [1-¹³C]lactate signals observed in vivo following injection of pre-polarized [1-¹³C]pyruvate has
Emilie A Bard-Chapeau et al.
Nature genetics, 46(1), 24-32 (2013-12-10)
The most common risk factor for developing hepatocellular carcinoma (HCC) is chronic infection with hepatitis B virus (HBV). To better understand the evolutionary forces driving HCC, we performed a near-saturating transposon mutagenesis screen in a mouse HBV model of HCC.
Sarah C Atkinson et al.
Plant molecular biology, 81(4-5), 431-446 (2013-01-29)
Lysine is one of the most limiting amino acids in plants and its biosynthesis is carefully regulated through inhibition of the first committed step in the pathway catalyzed by dihydrodipicolinate synthase (DHDPS). This is mediated via a feedback mechanism involving
Ching-An Wu et al.
Biochimica et biophysica acta, 1833(5), 1147-1156 (2013-02-05)
The Warburg effect is known to be crucial for cancer cells to acquire energy. Nutrient deficiencies are an important phenomenon in solid tumors, but the effect on cancer cell metabolism is not yet clear. In this study, we demonstrate that

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