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Merck
CN

E-006

EDDP perchlorate

ampule of 10 mg, certified reference material, Cerilliant®

别名:

EDDP perchlorate, 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine perchlorate

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关于此项目

经验公式(希尔记法):
C20H23N · HClO4
化学文摘社编号:
分子量:
377.86
MDL number:
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
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grade

certified reference material

Quality Level

form

solid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 10 mg

manufacturer/tradename

Cerilliant®

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

neat

storage temp.

−20°C

General description

A Certified Reference Material of the major urinary metabolite of methadone. Methadone, sold under various trade names such as Symoron, Amidone or Methadose®, is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. Suitable uses for this reference standard include as starting material in preparation of calibrators and controls for LC/MS or GC/MS methods in methadone testing for applications in clinical toxicology or forensic analysis.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Methadose is a registered trademark of Mallinckrodt Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany


pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - STOT SE 3

target_organs

Central nervous system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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M Rosa Boleda et al.
Chemosphere, 84(11), 1601-1607 (2011-06-15)
A total of seventy samples of drinking water were tested for non-controlled and illicit drugs. Of these, 43 were from Spanish cities, 15 from seven other European countries, three from Japan and nine from seven different Latin American countries. The
Matthias Gosselin et al.
Forensic science international, 209(1-3), 154-159 (2011-02-16)
This paper describes a sensitive UPLC-MS/MS method for quantification of methadone and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in single empty puparial case of Lucilia sericata. Larvae were reared on substrates spiked with different concentrations of methadone (0-4 μg/g). Methadone was quantified in puparia
Edijs Leimanis et al.
Journal of analytical toxicology, 36(4), 239-249 (2012-04-19)
Methadone is used to treat moderate to severe pain in patients not responsive to non-narcotic analgesics and for maintenance treatment of opioid addiction. Methadone is primarily metabolized by N-demethylation to an inactive metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene (EDDP) by CYP3A4 and CYP2B6. Establishing



全球贸易项目编号

货号GTIN
E-006-10MG04061833592298