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Merck
CN

H-027

(±)-11-羟基-Δ9-四氢大麻酚标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C21H30O3
化学文摘社编号:
分子量:
330.46
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
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grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

cannabis testing
forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

OC1=CC(CCCCC)=CC2=C1C3C=C(CO)CCC3C(O2)(C)C

InChI

1S/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h10-12,16-17,22-23H,4-9,13H2,1-3H3

InChI key

YCBKSSAWEUDACY-UHFFFAOYSA-N

General description

经认证的加标溶液®,适用于LC/MS或GC/MS应用,用于大麻素测试,尿液药物测试,临床毒理学或法医分析。11-羟基-Δ9-THC 是大麻主要精神活性成分(Δ9--四氢大麻酚 (Δ9-THC))的主要氧化代谢物。

Application

该认证加标溶液®适用于通过 HPLC、GC/MS 或 LC-MS/MS 法进行 (±)-11-羟基-Δ9-THC 测定,从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。该认证标准物质(CRM)还可作如下用途:
  • 使用超高效液相色谱(UHPLC)结合三重四极杆质谱法在液-液萃取后定量测定人血浆样品中的大麻二酚和 Δ9-四氢大麻酚,以及鉴定少量大麻素
  • 基于液相色谱-串联质谱(LC-MS/MS)法在固相萃取(SPE)后测定口服液样品中的 10 种大麻素
  • 通过气相色谱(GC)联合三重四极杆质谱仪分析血浆和尿液中 Δ9-四氢大麻酚(Δ9-THC)及其三种代谢物
  • 开发基于固相萃取(SPE)的自动样品制备方法,以使用液相色谱-质谱法(LC-MS)测定血清、唾液和尿液中 ∆9--四氢大麻酚(THC)及其三种主要代谢物
  • 通过大气压化学电离气相色谱-串联质谱法(APGC-MS/MS)同时测定人血清样品中的大麻素及其代谢物

Features and Benefits

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书(CoA),包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试,以确保准确性和保质期
  • 使用合格的精密天平进行重量准备,以确保最小不确定性
  • 氩气环境下火焰密封,装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式,以提高实验室效率

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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J Röhrich et al.
Journal of analytical toxicology, 34(4), 196-203 (2010-05-15)
Cannabinoid concentrations in blood and urine after passive exposure to cannabis smoke under real-life conditions were investigated in this study. Eight healthy volunteers were exposed to cannabis smoke for 3 h in a well-attended coffee shop in Maastricht, Netherlands. An
Cynthia Coulter et al.
Journal of analytical toxicology, 32(8), 653-658 (2008-11-15)
An analytical procedure for the determination of Delta9-tetrahydrocannabinol (THC), 11-nor-9-carboxy-Delta9-tetrahydrocannabinol (THCA), and 11-hydroxy-Delta9-tetrahydrocannabinol (11-OH-THC) in whole blood has been developed and validated using liquid chromatography with tandem mass spectral detection (MS). Cannabinoids present in the blood samples were quantified using
Erin L Karschner et al.
Analytical and bioanalytical chemistry, 397(2), 603-611 (2010-03-23)
A sensitive analytical method for simultaneous quantification of sub-nanogram concentrations of cannabidiol (CBD), Delta(9)-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OH-THC), and 11-nor-9-carboxy-THC (THCCOOH) in plasma is presented for monitoring cannabinoid pharmacotherapy and illicit cannabis use. Analytes were extracted from 1 mL plasma by



全球贸易项目编号

货号GTIN
H-027-1ML04061838055095