H-027
(±)-11-羟基-Δ9-四氢大麻酚标准液 溶液
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C21H30O3
化学文摘社编号:
分子量:
330.46
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
InChI key
YCBKSSAWEUDACY-UHFFFAOYSA-N
InChI
1S/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h10-12,16-17,22-23H,4-9,13H2,1-3H3
SMILES string
OC1=CC(CCCCC)=CC2=C1C3C=C(CO)CCC3C(O2)(C)C
grade
certified reference material
Quality Level
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
drug control
psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
cannabis testing
forensics and toxicology
format
single component solution
storage temp.
2-8°C
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General description
经认证的加标溶液®，适用于LC/MS或GC/MS应用，用于大麻素测试，尿液药物测试，临床毒理学或法医分析。11-羟基-Δ9-THC 是大麻主要精神活性成分（Δ9--四氢大麻酚 (Δ9-THC)）的主要氧化代谢物。
Application
该认证加标溶液®适用于通过 HPLC、GC/MS 或 LC-MS/MS 法进行 (±)-11-羟基-Δ9-THC 测定，从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。该认证标准物质（CRM）还可作如下用途：
- 使用超高效液相色谱（UHPLC）结合三重四极杆质谱法在液-液萃取后定量测定人血浆样品中的大麻二酚和 Δ9-四氢大麻酚，以及鉴定少量大麻素
- 基于液相色谱-串联质谱（LC-MS/MS）法在固相萃取（SPE）后测定口服液样品中的 10 种大麻素
- 通过气相色谱（GC）联合三重四极杆质谱仪分析血浆和尿液中 Δ9-四氢大麻酚（Δ9-THC）及其三种代谢物
- 开发基于固相萃取（SPE）的自动样品制备方法，以使用液相色谱-质谱法（LC-MS）测定血清、唾液和尿液中 ∆9--四氢大麻酚（THC）及其三种主要代谢物
- 通过大气压化学电离气相色谱-串联质谱法（APGC-MS/MS）同时测定人血清样品中的大麻素及其代谢物
Features and Benefits
- 完全符合 ISO/IEC 17025 和 ISO 17034 认证
- 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
- 通过实时稳定性研究严格测试，以确保准确性和保质期
- 使用合格的精密天平进行重量准备，以确保最小不确定性
- 氩气环境下火焰密封，装入安瓿以便长期保存
- 提供方便的 DEA 豁免格式，以提高实验室效率
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
J Röhrich et al.
Journal of analytical toxicology, 34(4), 196-203 (2010-05-15)
Cannabinoid concentrations in blood and urine after passive exposure to cannabis smoke under real-life conditions were investigated in this study. Eight healthy volunteers were exposed to cannabis smoke for 3 h in a well-attended coffee shop in Maastricht, Netherlands. An
Alex Straiker et al.
British journal of pharmacology, 165(8), 2660-2671 (2011-10-22)
Cannabinoids such as Δ(9) - tetrahydrocannabinol, the major psychoactive component of marijuana and hashish, primarily act via cannabinoid CB(1) and CB(2) receptors to produce characteristic behavioural effects in humans. Due to the tractability of rodent models for electrophysiological and behavioural
Stefan W Toennes et al.
Archiv fur Kriminologie, 225(3-4), 90-98 (2010-05-29)
When defendants are confronted with evidence of cannabinoids in their blood suggesting consumption of cannabis they sometimes argue that this could only be due to a passive exposure. The small number of controlled studies available showed that tetrahydrocannabinol (THC), the
Erin L Karschner et al.
Journal of analytical toxicology, 33(8), 469-477 (2009-10-31)
Delta(9)-Tetrahydrocannabinol (THC) is commonly found in toxicological specimens from driving under the influence and accident investigations. Plasma cannabinoid concentrations were determined in 18 long-term heavy cannabis smokers residing on an in-patient research unit for seven days of monitored abstinence. THC
Ross H Lowe et al.
Drug and alcohol dependence, 105(1-2), 24-32 (2009-07-28)
Generally, urinary 11-nor-9-carboxy-Delta9-tetrahydrocannabinol (THCCOOH) after alkaline hydrolysis is monitored to detect cannabis exposure, although last use may have been weeks prior in chronic cannabis users. Delta9-Tetrahydrocannabinol (THC) and 11-hydroxy-THC (11-OH-THC) concentrations in urine following Escherichia coli beta-glucuronidase hydrolysis were proposed
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