跳转至内容
Merck
CN

A-094

Supelco

Ascomycin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

登录查看公司和协议定价

关于此项目

经验公式（希尔记法）:
C43H69NO12
CAS Number:
104987-12-4
分子量:
792.01
EC 号:
200-835-2
UNSPSC代码:
41116107
NACRES:
NA.24

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

等级

certified reference material

质量水平

300

表单

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in acetonitrile

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

包装形式

single component solution

储存温度

−70°C

SMILES字符串

CCC1\C=C(C)\CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)\C(C)=C\C4CCC(O)C(C4)OC

InChI

1S/C43H69NO12/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)44-16-12-11-13-31(44)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-32(45)35(22-29)52-7/h18,20,25,27-33,35-39,45-46,51H,10-17,19,21-23H2,1-9H3/b24-18+,26-20+

InChI key

ZDQSOHOQTUFQEM-AMASXYNMSA-N

相关类别

一般描述

An internal standard for LC-MS/MS testing of the immunosuppressants tacrolimus, sirolimus, and everolimus. Certified Spiking Solutions® are suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays to ensure patients remain within the narrow therapeutic range of these immunosuppressants. The Snap-N-Spike® format provides laboratories the ability to spike into their matrix of choice just before use and allows them to eliminate weighing operations of hazardous substances which significantly reduces occupational exposure hazards related to handling acutely toxic powders such as immunosuppressants.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

35.6 °F - closed cup

闪点(°C)

2 °C - closed cup

法规信息

危险化学品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Xiao-ling Qin et al.
Biomedical chromatography : BMC, 24(4), 399-405 (2009-08-21)
A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method was developed and validated for determining tacrolimus (FK506) in rat tissues to study the effect of Schisandra sphenanthera extract on FK506 tissue distribution. After a liquid-liquid extraction with ethyl acetate, FK506 and ascomycin
Jane R Allison et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 10(18), 3213-3228 (2009-11-03)
Experimentally measured values of molecular properties or observables of biomolecules such as proteins are generally averages over time and space, which do not contain sufficient information to determine the underlying conformational distribution of the molecules in solution. The relationship between
K Hoogtanders et al.
Journal of pharmaceutical and biomedical analysis, 44(3), 658-664 (2006-12-23)
In a preliminary investigation an assay for tacrolimus based on fingerprick sampling and consecutive application as a blood spot on sampling paper has been developed. The dried blood spot was analysed by HPLC-tandem mass spectrometry. The validated range was 1-30
Nitin S Patil et al.
Journal of chromatography. A, 1177(2), 234-242 (2007-11-03)
In preparative chromatography, often the solubility of the sample in the mobile phase is limited, making the mobile phase unsuitable as a solvent for preparation of load. Generally, solvents that have high solubility for the sample also have higher elution
Chemistry of the immunomodulatory macrolide ascomycin and related analogues.
Murty A R C Bulusu et al.
Progress in the chemistry of organic natural products, 94, 59-126 (2011-08-13)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持