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经验公式(希尔记法):
C16H14FN3O
化学文摘社编号:
分子量:
283.30
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
产品名称
7-氨基氟硝西泮标准液 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
InChI key
LTCDLGUFORGHGY-UHFFFAOYSA-N
InChI
1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3
SMILES string
FC1=CC=CC=C1C2=NCC(N(C)C3=CC=C(N)C=C23)=O
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
Quality Level
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General description
As a major metabolite of flunitrazepam, 7-aminoflunitrazepam is a biomarker for use of the parent drug. Flunitrazepam is an intermediate-acting benzodiazepine, typically used in the treatment of severe insomnia. This certified solution standard is suitable for numerous GC/MS or LC/MS testing applications in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2.0 °C - closed cup
法规信息
危险化学品
此项目有
Dong-Liang Lin et al.
Journal of analytical toxicology, 29(7), 718-723 (2006-01-20)
With 7-aminoflunitrazepam (7-amino-FM2)-specific ELISAs now readily available from several commercial sources (e.g., Cozart Bioscience, Immunalysis, this study was conducted to evaluate the performance characteristics of these products when applied to the two-step testing protocol as commonly practiced in today's workplace
Stéphane Pirnay et al.
Toxicological sciences : an official journal of the Society of Toxicology, 106(1), 64-73 (2008-08-16)
High-dosage buprenorphine (BUP) consumed concomitantly with benzodiazepines (BZDs) including flunitrazepam (FZ) may cause life-threatening respiratory depression despite a BUP ceiling effect and BZDs' limited effects on ventilation. However, the mechanism of BUP/FZ interaction remains unknown. We hypothesized that BUP may
Franz E Dussy et al.
International journal of legal medicine, 120(6), 323-330 (2005-10-13)
A high-performance liquid chromatography method for the determination of benzodiazepines and their metabolites in whole blood and serum using mass spectrometry (MS) and photodiode array (PDA) detection is presented. The combination of both detection types can complement each other and
Robert Kronstrand et al.
Forensic science international, 145(2-3), 183-190 (2004-09-29)
Analyzing hair for many substances can be tedious and expensive, and a rapid screening method should prove helpful. Generally, screening has been performed using immunological tests, mainly in workplace drug testing, where the number of samples has been high. The
A fatal case due to combined toxicity of psychotropic drugs.
Hiroshi Kinoshita et al.
Forensic science international, 181(1-3), e7-e8 (2008-09-27)
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