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关于此项目
经验公式(希尔记法):
C16H14FN3O
化学文摘社编号:
分子量:
283.30
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
InChI key
LTCDLGUFORGHGY-UHFFFAOYSA-N
InChI
1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3
SMILES string
FC1=CC=CC=C1C2=NCC(N(C)C3=CC=C(N)C=C23)=O
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
Quality Level
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General description
As a major metabolite of flunitrazepam, 7-aminoflunitrazepam is a biomarker for use of the parent drug. Flunitrazepam is an intermediate-acting benzodiazepine, typically used in the treatment of severe insomnia. This certified solution standard is suitable for numerous GC/MS or LC/MS testing applications in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Franz E Dussy et al.
International journal of legal medicine, 120(6), 323-330 (2005-10-13)
A high-performance liquid chromatography method for the determination of benzodiazepines and their metabolites in whole blood and serum using mass spectrometry (MS) and photodiode array (PDA) detection is presented. The combination of both detection types can complement each other and
Yi-Chi Ho et al.
Analytica chimica acta, 697(1-2), 1-7 (2011-06-07)
Despite the advantages of simplicity and high-throughput detection that matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has over other methods, quantitative analysis of low-molecular-weight analyte is hampered by interference from matrix-derived background noise and signal fluctuation due to the
Robert Kronstrand et al.
Forensic science international, 145(2-3), 183-190 (2004-09-29)
Analyzing hair for many substances can be tedious and expensive, and a rapid screening method should prove helpful. Generally, screening has been performed using immunological tests, mainly in workplace drug testing, where the number of samples has been high. The
A fatal case due to combined toxicity of psychotropic drugs.
Hiroshi Kinoshita et al.
Forensic science international, 181(1-3), e7-e8 (2008-09-27)
I Gafni et al.
Journal of clinical psychopharmacology, 23(2), 169-175 (2003-03-18)
Flunitrazepam, a hypnotic benzodiazepine, is widely prescribed around the world for the treatment of insomnia and as a preanesthetic. In vitro studies have shown that the metabolism of flunitrazepam to desmethylflunitrazepam and 3-hydroxyflunitrazepam is mediated in part by the polymorphic
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