A-916
7-氨基氯硝西泮标准液 溶液
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C15H12ClN3O
化学文摘社编号:
分子量:
285.73
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20)
SMILES string
NC1=CC=C2C(C(C3=C(Cl)C=CC=C3)=NCC(N2)=O)=C1
InChI key
HEFRPWRJTGLSSV-UHFFFAOYSA-N
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
2-8°C
Quality Level
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General description
该认证的Snap-N-Spike®溶液，适合作为法医分析、临床毒理学和尿液药物检测的许多GC/MS或LC/MS应用中校准物或对照品中的起始材料。作为主要代谢产物，7-氨基氯硝西泮可用于监测母体药物氯硝西泮的使用。以Klonopin®和Rivotril出售的氯硝西泮是一种长效苯二氮卓类药物，具有抗焦虑、抗惊厥、肌肉松弛和催眠作用。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Klonopin is a registered trademark of Hoffmann-La Roche Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
危险化学品
此项目有
Albert A Elian
Forensic science international, 134(1), 54-56 (2003-07-05)
The ability of five commercially available enzyme-linked immunosorbent assay (ELISA) benzodiazepines to detect clonazepam and 7-aminoclonazepam in blood and urine was investigated. To determine the cross-reactivity of various ELISA assays, drug free blood and urine were fortified with clonazepam and
Adam Negrusz et al.
Journal of analytical toxicology, 26(7), 471-478 (2002-11-09)
The objective of this paper was to determine whether benzodiazepine clonazepam (CLO) and its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in hair collected from healthy volunteers after receiving a single 3-mg dose of Klonopin (clonazepam). Such data would be
I Petters et al.
Journal of chromatography, 306, 241-248 (1984-03-09)
A high-performance liquid chromatographic method is reported for the determination of clonazepam and its metabolites 7-amino- and 7-acetamidoclonazepam. Extraction from buffered plasma is carried out at pH 9.5 with hexane-ethyl acetate (7:3) for clonazepam and with chloroform for the metabolites.
Adam Negrusz et al.
Analytical and bioanalytical chemistry, 376(8), 1198-1204 (2003-07-08)
The objective of this paper was to determine how long after administration of benzodiazepine clonazepam (CLO), its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in urine collected from 10 healthy volunteers who received a single 3-mg dose of Klonopin (clonazepam).
Anni Steentoft et al.
Forensic science international, 184(1-3), 74-79 (2009-01-20)
The benzodiazepine clonazepam is a prescription drug used to treat epilepsy and anxiety. In addition, it is frequently used to treat drug addicts and is itself a popular drug of abuse. In this study, we report the incidence and blood
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