B-043
Brompheniramine maleate solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C20H23BrN2O4
化学文摘社编号:
分子量:
435.31
UNSPSC Code:
41116107
MDL number:
NACRES:
NA.24
EC Number:
200-659-6
InChI key
SRGKFVAASLQVBO-BTJKTKAUSA-N
InChI
1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES string
OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccc(Br)cc1)c2ccccn2
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
pharmaceutical (small molecule)
format
single component solution
storage temp.
−20°C
Quality Level
Gene Information
human ... HRH1(3269)
General description
Brompheniramine is an over-the-counter antihistamine sold under the trade names Bromfed®, Dimetapp®, and Lodrane®. The drug is indicated for treatment of the common cold and allergic rhinitis symptoms including runny nose and itchy eyes. This Snap-N-Spike® Reference Solution is suitable for use as starting material in calibrators or controls for LC/MS or GC/MS methods in clinical toxicology, forensic analysis, and pharmaceutical research.
Legal Information
Bromfed is a registered trademark of Wockhardt EU Operations Swiss AG
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Dimetapp is a registered trademark of Wyeth LLC
Lodrane is a registered trademark of ECR Pharmaceuticals Co., Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Giorgia De Paoli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(31), 3771-3774 (2011-11-08)
The increased availability of new psychoactive substances ("legal highs") from retail shops or internet sources has caught the imagination of consumers, law enforcement and scientific communities. The present study describes the identification of 2-(diphenylmethyl)pyrrolidine (DPMP, desoxy-D2PM) as the key constituent
Jozef Marák et al.
Journal of pharmaceutical and biomedical analysis, 46(5), 870-876 (2007-07-10)
The present work illustrates potentialities of on-line combined isotachophoresis-capillary zone electrophoresis (ITP-CZE) separation techniques coupled with on-capillary diode array detector (DAD) for enantiomeric purity testing of drugs in pharmaceuticals. The general advantages of the proposed method are its (i) high
Ziyaur Rahman et al.
International journal of pharmaceutics, 422(1-2), 91-100 (2011-11-01)
The aim of this investigation was to evaluate the complexation potential of brompheniramine maleate (BPM) and tannic acid (TA) for sustained release and taste masking effects. The complexes (1:1-1:7 TA to BPM ratio) were prepared by the solvent evaporation method
H Hashem et al.
Die Pharmazie, 63(4), 256-262 (2008-05-13)
In this study we have examined the effect of achiral water soluble p-sulfonatocalixarenes (SCX[n]) on chiral separation propranolol-HCl and brompheniramine maleate. Several cyclodextrins (CDs) and cyclodextrin derivatives were examined as chiral selectors applying complete filling technique (CFT) accompanied with the
Warren C Rodrigues et al.
Journal of analytical toxicology, 36(2), 123-129 (2012-02-18)
Diphenhydramine (DPH) is a common over the counter antihistamine that produces drowsiness and has the potential to cause driving under the influence of drugs-related accidents. To date there are no commercially available immunoassay screening kits for its detection in biological
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