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C-015

可待因标准液溶液

Name: 可待因标准液 溶液
Brand: CERILLIAN

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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关于此项目

经验公式（希尔记法）:

C₁₈H₂₁NO₃

化学文摘社编号:

76-57-3

分子量:

299.36

UNSPSC Code:

41116107

MDL number:

MFCD06764379

NACRES:

NA.24

EC Number:

200-659-6

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属性

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE^®, SNAP-N-SHOOT^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal); Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

COc1ccc2C[C@@H]3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1

InChI key

OROGSEYTTFOCAN-DNJOTXNNSA-N

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)

说明

General description

可待因是一种具有镇痛、镇咳和镇静作用的阿片类药物，是鸦片中第二大主要生物碱。此认证参考溶液作为校准物或对照品中的起始材料，用于临床毒理学、法医分析、制药研究和止痛处方监测等的各种LC/MS或GC/MS检验方法。作为一种广泛流行的消遣性药物，可待因在澳大利亚、新西兰、罗马尼亚、瑞典和美国等国家受到了多种麻醉品管制法的监管。由于鸦片被归类为受控物质，Cerrilliant都是以免DEA溶液的形式提供绝大多数鸦片参考标准品的，这带来了更高的便利性。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品

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Mladen V Tzvetkov et al.

Biochemical pharmacology, 86(5), 666-678 (2013-07-10)

We investigated whether morphine and its pro-drug codeine are substrates of the highly genetically polymorphic organic cation transporter OCT1 and whether OCT1 polymorphisms may affect morphine and codeine pharmacokinetics in humans. Morphine showed low transporter-independent membrane permeability (0.5 × 10⁻⁶

Platelet-activating factor (PAF) induces wheal and flare skin reactions independent of mast cell degranulation.

K Krause et al.

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Platelet-activating factor (PAF) causes wheal and flare responses which are abrogated by H1-antihistamines giving rise to the hypothesis that PAF-induced wheal development is secondary to histamine release from dermal mast cells. But is this hypothesis correct? Wheal and flare responses

Is it farewell to codeine?

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全球贸易项目编号

货号	GTIN
C-015-1ML	04061833444436