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Merck
CN

C-046

大麻酚标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C21H26O2
化学文摘社编号:
分子量:
310.43
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
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产品名称

大麻酚标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

VBGLYOIFKLUMQG-UHFFFAOYSA-N

InChI

1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3

SMILES string

CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

cannabis testing
cannabis testing

format

single component solution

storage temp.

−20°C

Quality Level

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Legal Information

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

该认证标准物质(CRM)还可作如下用途:
  • 使用反相高效液相色谱(RP-HPLC)结合二极管阵列检测器(DAD)估算油基质中放入 4 种大麻素
  • 根据国际药品注册协调会议(ICH)分析方法验证三方指南,通过 HPLC-UV 方法对不同大麻品种的生物质和提取物中的 11 种大麻素进行同步分析
  • 使用反相高压液相色谱(RP-HPLC)结合 UV 检测器测定 8 种大麻样品和 12 种法医大麻样品中的 8 种大麻素
  • 采用高效液相色谱法(HPLC)结合 UV 检测分析大麻干花中 9 种大麻素的含量
  • 开发并验证一种超高效液相色谱(UHPLC)方法,结合光电二极管阵列和质谱检测器测定各种大麻样品中的 11 种大麻素
  • 根据 AOAC 和 ASTM 大麻和大麻基质指南,通过 LC-MS/MS 在固相萃取后对大麻和大麻样品中的 17 种大麻素进行定量分析

Features and Benefits

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书(CoA),包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试,以确保准确性和保质期
  • 使用合格的精密天平进行重量准备,以确保最小不确定性
  • 氩气环境下火焰密封,装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式,以提高实验室效率

General description

这种认证的峰值溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 进行大麻酚测试,从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。

大麻酚是一种植物大麻素,属于 C21 萜类化合物。它存在于大麻植物中,也是 Δ9-THC(大麻的主要精神活性成分)的代谢产物。大麻酚还是暴露于空气和光线下四氢大麻酚降解的主要产物。

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
Krishna Prasad Bastola et al.
Planta medica, 73(3), 273-275 (2007-03-14)
Cannabinoids, the main constituents of the cannabis plant, are being increasingly studied for their medicinal properties. Cannabinolic acid (CBNA; 1) was synthesized from tetrahydrocannabinolic acid (THCA; 2), a major constituent of the cannabis plant, by aromatization using selenium dioxide mixed
F Van der Kooy et al.
Inhalation toxicology, 21(2), 87-90 (2008-10-16)
Medicinal cannabis has attracted a lot of attention in recent times. Various forms of administration are used, of which smoking is very common but the least desirable. Smoking cannabis generates a large amount of unwanted side products, of which carcinogenic
Dinesh Thapa et al.
European journal of pharmacology, 650(1), 64-71 (2010-10-19)
Both natural and synthetic cannabinoids have been shown to suppress the growth of tumor cells in culture and in animal models by affecting key signaling pathways including angiogenesis, a pivotal step in tumor growth, invasion, and metastasis. In our search
Satoshi Yamaori et al.
Drug metabolism and pharmacokinetics, 27(3), 294-300 (2011-12-15)
Inhibitory effects of Δ⁹-tetrahydrocannabinol (Δ⁹-THC), cannabidiol (CBD), and cannabinol (CBN), the three major constituents in marijuana, and polycyclic aromatic hydrocarbons (PAHs) contained in marijuana smoke on catalytic activity of human cytochrome P450 (CYP) 2C9 were investigated. These phytocannabinoids concentration-dependently inhibited

商品

ISO-certified cannabinoid CRMs, THC and THCA, available as single components or mixes, for accurate potency testing.

A complete workflow for the HPLC separation of 17 cannabinoids in different cannabis products using Ascentis® Express C18 Column in a shorter run time with retention time stability. Learn more here.

Overview of gradient HPLC-based cannabinoid analysis optimized for key method parameters.

HPLC-DAD workflow analyzes 14 cannabinoids in hemp extracts in 10 minutes using Chromolith columns for robust performance.

查看所有结果

实验方案

HPLC separation of 17 important cannabinoids including CBD, delta 9 THC and THCA. Read the application note.

Rapid potency testing of marijuana-infused edibles using LC/MS on a biphenyl stationary phase detected eleven cannabinoids.

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